Evidence map›Paper›PMID 42395431›Full record

ArticlebioRxiv : the preprint server for biology2026

Altered Lighting Conditions Elicit Sex-Specific Circadian Behaviors in Diurnal Grass Rats.

Jeremiah Hartner, Noah Muscat, Mujtaba Khan, Katrina Linning-Duffy, Diksha Zutshi, Nicolette Ognjanovski, Lily Yan, Brendon O Watson

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jeremiah HartnerWatson Laboratory, Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0002-0270-3311
Noah MuscatWatson Laboratory, Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA.
Mujtaba KhanWatson Laboratory, Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA.
Katrina Linning-DuffyYan Laboratory, Department of Psychology, Michigan State University, East Lansing, MI, USA.
Diksha ZutshiWatson Laboratory, Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA.
Nicolette OgnjanovskiWatson Laboratory, Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0002-0807-7526
Lily YanYan Laboratory, Department of Psychology, Michigan State University, East Lansing, MI, USA.ORCID 0000-0002-6261-2542
Brendon O WatsonWatson Laboratory, Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0002-9940-4579

Funding

Electrophysiologic characterization of circadian rhythms of prefrontal cortical network states in a diurnal rodentR21MH131527 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WATSON, BRENDON O · 2023 to 2024
$443k
NIMH NIH HHS R21 MH131527
6 · The paper itself

Abstract

Circadian rhythms are crucial to biological functions, and cognitive functions such as attention, choice, and preference-related behaviors are modulated by circadian rhythms and disrupted in mood disorders such as Seasonal Affective Disorder (SAD) and Major Depressive Disorder (MDD). These neuropsychiatric diseases can be induced or worsened by alterations to daily light patterns and can also be treated with circadian-timed bright-light therapy, suggesting modulatory effects of light brightness on mood and behavior. While most laboratory rodents are nocturnal, the Nile grass rat (Arvicanthis niloticus) is diurnal, offering a unique model to study light modulation effects relevant to humans. In this work, we track daily activity in male and female grass rats under varied lighting for several weeks, revealing sex-specific circadian patterns and responses. These findings establish a foundation for mechanistic studies of light effects on mood-related brain circuits in diurnal animals.

Indexed as

actigraphyArvicanthis niloticusCircadian rhythmsdiurnalMajor Depressive DisorderNile grass ratSeasonal Affective Disorder

Identifiers

PMID42395431
PMCPMC13320902

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.