ArticlebioRxiv : the preprint server for biology2026
Distinct nanoscale architectures of GABAergic inhibitory synapses predict diverse synaptic output.
Amber R Stewart, Sara E Gookin, Joshua D Garcia, Kevin C Crosby, Katharine R Smith
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
5 authors.
Amber R StewartDepartment of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO 80045.
Sara E GookinDepartment of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO 80045.
Joshua D GarciaDepartment of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO 80045.
Kevin C CrosbyDepartment of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO 80045.
Katharine R SmithDepartment of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO 80045.ORCID 0000-0002-4762-7201 Funding
University of Colorado Anschutz Medical Campus DRCP30DK116073 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI JANE E REUSCH · 2020 to 2026
$10.8MPREDOCTORAL TRAINING PROGRAM IN PHARMACOLOGYT32GM007635 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI DELL'ACQUA, MARK L · 1985 to 2023
$6.1MLocal translation mechanisms to control inhibitory synaptic plasticityR01MH128199 · NIMH · UNIVERSITY OF COLORADO DENVER · PI SMITH, KATHARINE RACHEL · 2022 to 2025
$2.5MNanoscale organization of the inhibitory synapse during synaptic plasticityR01MH119154 · NIMH · UNIVERSITY OF COLORADO DENVER · PI SMITH, KATHARINE RACHEL · 2020 to 2024
$2.0MThe role of subsynaptic nanoscale architecture in inhibitory synaptic plasticityF31NS141320 · NINDS · UNIVERSITY OF COLORADO DENVER · PI Amber Rose Stewart · 2025 to 2026
$75kUnderstanding the temporal regulation of inhibitory synapse depression and elimination in the context of cerebral ischemiaF99NS120640 · NINDS · UNIVERSITY OF COLORADO DENVER · PI GARCIA, JOSHUA DAYLON · 2021 to 2022
$72kNIDDK NIH HHS P30 DK116073NIGMS NIH HHS T32 GM007635NIMH NIH HHS R01 MH119154NIMH NIH HHS R01 MH128199NINDS NIH HHS F31 NS141320NINDS NIH HHS F99 NS120640
6 · The paper itselfAbstract
GABAergic synaptic inhibition is heterogenous across neuronal compartments, and plays a critical role in shaping local, cellular and circuit excitability. In pyramidal neurons, inhibition is mediated by GABAA receptors (GABA
Indexed as
Biological SciencesClassificationGABAA receptorgephyrinInhibitory synapseMajorMinornano-architectureNeuroscience
Identifiers
PMID42395548
PMCPMC13320784
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