ReviewFood & nutrition research2026
Influence of diet on the modulation of gut microbiota and its neurobiological effects on cognition: a systematic review and meta-analysis.
Review in Food & nutrition research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: The gut microbiota, a key regulator of the gut-brain axis, is profoundly influenced by diet, and its modulation through dietary patterns may play a critical role in mitigating mild cognitive impairment (MCI). Objective: To evaluate whether dietary interventions modify gut microbiota composition in individuals with MCI and to determine whether these microbiota changes are associated with variations in cognitive function. Methods: A systematic review and meta-analysis were conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. Randomized clinical trials and observational studies evaluating dietary exposures, gut microbiota, and cognitive outcomes in adults with MCI were included. Data extraction and risk-of-bias assessment were performed using standardized and validated tools. When applicable, pooled effects on cognition were estimated using random-effects models and between-study heterogeneity was quantified. Results: Of 3,029 records identified, 11 studies met the inclusion criteria (nine randomized trials and two observational studies), with a weighted mean age of 65.24 years. Gut microbiota differed between normal cognition and MCI-beneficial taxa (e.g. Conclusion: This review highlights the potential role of diet in modulating gut microbiota and its impact on cognition in MCI, emphasizing the need for standardized interventions and further research to clarify the underlying mechanisms.
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