ArticleWorld journal of nephrology2026
Comparison of carotid intima-media thickness between hemodialysis and peritoneal dialysis patients.
Article in World journal of nephrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundPatients with chronic kidney disease (CKD) are at high risk of developing cardiovascular disease (CVD). Carotid intima-media thickness (cIMT) is a strong predictor of CVD. Klotho has been associated with increased atherosclerotic plaque stability in CKD patients.
aimTo investigate the association between dialysis modality and cIMT in dialysis patients.
methodsA cross-sectional study of 83 dialysis patients, 40 hemodialysis (HD) patients and 43 peritoneal dialysis (PD) patients, who met the inclusion criteria. Anamnesis, carotid artery ultrasonography (USG), and laboratory tests were performed on all patients. cIMT measurements were performed in 6 carotid territories using arterial USG.
resultsPD patients had lower cIMT [0.53 (0.47; 0.67)
conclusionThis study showed that PD patients have lower cIMT than HD patients. Younger age was independently associated with lower cIMT. On the other hand, FGF-23 and the FGF-23/Klotho ratio were significantly positively correlated with CaxP product in PD patients, but not in HD patients. Klotho reduces the strength of this correlation, thus appearing play an important role in the lower cIMT in these PD patients.
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