ReviewChinese medical journal pulmonary and critical care medicine2026
Molecular mechanisms and therapeutic targets in lung cancer-nerve crosstalk.
Review in Chinese medical journal pulmonary and critical care medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- The Role of the Nervous System in Lung Disease.Current neurology and neuroscience reports · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Reciprocal crosstalk between the nervous system and malignancies is increasingly recognized as a key regulator of tumor progression across solid cancers. Neuronal activity and nerve infiltration can shape tumor growth, immune tone, and metastatic behavior through paracrine signaling and, in selected contexts, synapse-like interactions. However, how neural circuits regulate lung cancer progression remains insufficiently defined. β-adrenergic blockade has been reported to be associated with reduced lung tumor growth and metastatic potential in multiple settings, highlighting the clinical relevance of innervation. Here we synthesize emerging evidence on lung cancer-nerve crosstalk from the perspective of cancer neuroscience, focusing on neural remodeling in the tumor microenvironment, mechanisms underlying tumorigenesis and metastasis, the neuro-immune-tumor axis, and translational opportunities for neuro-modulatory interventions. This review provides an integrated framework to inform future mechanistic studies and the development of therapeutically actionable targets.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.