ArticleJournal of intensive medicine2026
Timing of veno-arterial extracorporeal membrane oxygenation in cardiogenic shock: A systematic review and meta-analysis.
Article in Journal of intensive medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Although the use of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) in cardiogenic shock has increased, the optimal timing for its initiation is still unclear. This study aimed to evaluate whether early initiation of VA-ECMO in patients with cardiogenic shock is associated with improved outcomes compared with delayed initiation. Methods: This systematic review and meta-analysis was prospectively registered in PROSPERO (CRD42025635381). We searched PubMed, Embase, and the Cochrane Library from their inception to December 11, 2024, to identify published studies that compared early Results: Eight observational studies involving 10,451 patients were included. Early VA-ECMO initiation was associated with reduced short-term mortality compared to delayed initiation (OR=0.74, 95% CI: 0.58 to 0.96, Conclusions: Early initiation of VA-ECMO in patients with cardiogenic shock appears to be associated with reduced short-term mortality without an apparent increase in neurological, bleeding, or ischemic complications. As all included studies were observational, randomized controlled trials are needed to determine the optimal timing and patient selection for VA-ECMO initiation.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.