Evidence map›Paper›PMID 42396432›Full record

ReviewFrontiers in immunology2026

Antitumor effects of acupuncture and moxibustion: from immune modulation to tumor microenvironment remodeling.

Yinan Li, Xia Gao, Tian He, Benxu Ma, Yonghui Zhao

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yinan LiDepartment of Pathology, Qingdao Traditional Chinese Medicine Hospital, Qingdao Hiser Hospital Affiliated of Qingdao University, Qingdao, China.
Xia GaoDepartment of Acupuncture and Moxibustion, Qingdao Central Hospital, University of Health and Rehabilitation Sciences, (Qingdao Central Hospital), Qingdao, China.
Tian HeDepartment of Acupuncture and Moxibustion, Qingdao Central Hospital, University of Health and Rehabilitation Sciences, (Qingdao Central Hospital), Qingdao, China.
Benxu MaDepartment of Acupuncture and Moxibustion, Qingdao Central Hospital, University of Health and Rehabilitation Sciences, (Qingdao Central Hospital), Qingdao, China.
Yonghui ZhaoDepartment of Acupuncture and Moxibustion, Qingdao Central Hospital, University of Health and Rehabilitation Sciences, (Qingdao Central Hospital), Qingdao, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acupuncture and moxibustion are evidence - based modalities derived from traditional Chinese medicine. They employ strategic needle insertion or moxa - derived thermal stimulation at specific acupoints to ameliorate pathological conditions. Robust clinical data have validated their efficacy in mitigating gastrointestinal dysfunction, chemotherapy - induced neuropathy, cancer - related fatigue, and radiation - induced xerostomia. Crucially, within immunosuppressive tumor microenvironments (TME), these interventions exert direct antitumor effects through multimodal immunomodulation (1): Potentiation of innate immunity via enhanced cytotoxicity of

Indexed as

Acupuncture TherapyImmunomodulationMoxibustionNeoplasmsTumor MicroenvironmentAnimalsHumansacupunctureantitumor effectimmunologic mechanismmoxibustiontumor immune microenvironment

Identifiers

PMID42396432
PMCPMC13323237

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.