ArticleResearch square2026
Multiplexed video hyperspectral microendoscopy reveals tumor-immune dynamics in vivo.
Bryan Spring, Mohammad Saad, Rebecca Harman, Eric Kercher, Ryan Lang, Kai Zhang, Julia Tatz, Qianqian Fang, Jason Sutin, Zhiming Mai and 2 more
Abstract readPreprint
In one paragraphArticle in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
12 authors.
Rebecca HarmanNortheastern Univerisity.
Eric KercherUniversity of Massachusetts.
Ryan LangNortheastern Univerisity.
Julia TatzBoston Children's Hospital.
Qianqian FangNortheastern University.
Zhiming MaiMassachusetts General Hospital.
Akilan PalanisamiMassachusetts General Hospital.
Funding
Small Molecule Enhancers of Photodynamic Therapy for Skin CancerP01CA084203 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI Brian William Pogue · 2001 to 2026
$27.9MCenter for Innovation in Point of Care Technologies for the Future of Cancer CareU54EB015403 · NIBIB · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI KLAPPERICH, CATHERINE M. · 2012 to 2016
$8.9MMultiplexed and dynamically targeted photoimmunotherapy of heterogeneous, chemoresistant micrometastases guided by online in vivo optical imaging of cell-surface biomarkersR01CA226855 · NCI · NORTHEASTERN UNIVERSITY · PI SPRING, BRYAN QUILTY · 2020 to 2024
$3.1MTargeted Photoactivable Nanocells: Image-based Drug Delivery and Dosimetry in GBMR01CA156177 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI HASAN, TAYYABA, POGUE, BRIAN WILLIAM · 2011 to 2015
$2.5MHeterocellular 3D ovarian tumor arrays for imaging and mechanistic combinationsR01CA158415 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI HASAN, TAYYABA · 2012 to 2016
$2.0MOvarian Cancer PDT: Multi-intracellular targeting and Image-guided dosimetryR01CA160998 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI HASAN, TAYYABA · 2011 to 2015
$2.0MOnline monitoring and image-guided treatment of chemoresistant micrometastasesK22CA181611 · NCI · NORTHEASTERN UNIVERSITY · PI SPRING, BRYAN QUILTY · 2015 to 2017
$559kHyperspectral Microendscopy to Monitor VEGF During Pancreatic Cancer TherapyF32CA144210 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI SPRING, BRYAN QUILTY · 2010 to 2012
$153kNCI NIH HHS F32 CA144210NCI NIH HHS K22 CA181611NCI NIH HHS P01 CA084203NCI NIH HHS R01 CA156177NCI NIH HHS R01 CA158415NCI NIH HHS R01 CA160998NCI NIH HHS R01 CA226855NIBIB NIH HHS U54 EB015403
6 · The paper itselfAbstract
Tumor-immune interactions evolve dynamically within heterogeneous tumor microenvironments, yet methods for repeatedly measuring multiple cellular phenotypes
Identifiers
PMID42396523
PMCPMC13321235
What Socratic holds
Textmetadata
LicenceCC BY
Read underepoch 390