Evidence map›Paper›PMID 42396789›Full record

ArticleJournal of the American Heart Association2026

Academic Achievements in Adolescents With Congenital Heart Disease: A Total Population-Based Cohort Study.

Sofia Ekmark Sergel, Michael Lundberg, Cecilia Magnusson, Ulrika Ådén, Gunnar Bergman, Veronica Siljehav

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sofia Ekmark SergelDepartment of Women's & Children's Health Karolinska Institutet Stockholm Sweden.ORCID 0009-0000-1509-5645
Michael LundbergDepartment of Global Public Health Karolinska Institutet Stockholm Sweden.ORCID 0009-0000-2409-023X
Cecilia MagnussonDepartment of Global Public Health Karolinska Institutet Stockholm Sweden.ORCID 0000-0002-8567-6725
Ulrika ÅdénDepartment of Women's & Children's Health Karolinska Institutet Stockholm Sweden.ORCID 0000-0002-0650-3173
Gunnar Bergman *Department of Women's & Children's Health Karolinska Institutet Stockholm Sweden.ORCID 0000-0003-1619-0171
Veronica Siljehav *Department of Women's & Children's Health Karolinska Institutet Stockholm Sweden.ORCID 0009-0004-7763-7760

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImproved survival in children with congenital heart disease (CHD) has unveiled associated long-term neurodevelopmental impairments. However, the long-term effects on academic performance and the influence of sex, family, socioeconomic factors, and surgical era remain understudied, limited by small and incomplete cohorts.

methodsThis total-population cohort study with nested sibling analysis included all singletons born in Sweden between 1987 and 2005 who had complete socioeconomic data and resided in Sweden at age 16 years. Academic achievement at age 16 was assessed by upper secondary school qualification. Poisson and logistic regression were used to estimate adjusted prevalences, risk ratios, and risk differences. Adjustments were made for year of birth and socioeconomic status. Stratification by noncardiac congenital anomalies, sex, and surgical era was performed.

resultsOf 1 800 477 singletons included, 16 075 (0.9%) had CHD, classified hierarchically as univentricular heart (n=349), severe (n=1939), moderate (n=1764), or mild CHD (n=12 023). After excluding major noncardiac congenital anomalies, the adjusted risk difference for failing to meet upper secondary school qualification compared with children without CHD was 11 (95% CI, 5-17), 7 (95% CI, 4-9), 6 (95% CI, 3-8), and 2 (95% CI, 2-3) additional children per 100 for univentricular heart, severe, moderate, and mild CHD, respectively. Children with both CHD and noncardiac anomalies had poorer academic outcomes than those with CHD alone. Findings were consistent in sibling analyses and over time.

conclusionsAdolescents with CHD inherently face poorer academic performance, worsening with disease severity and persisting over time.

Indexed as

Academic SuccessHeart Defects, CongenitalAdolescentFemaleHumansMaleRisk FactorsSwedenacademic successcohort studiescongenital heart defectssiblingsuniventricular heart

Identifiers

PMID42396789
PMCPMC13477408

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.