Evidence mapPaperPMID 42397059Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

EpCAM

Byeonggeol Mun, Jinyoung Kim, Chang Gon Kim, Seokhyeong Go, Mina Han, Yujin Ouck, Soojin Jang, Seong Uk Son, Gamin Kim, Wonrak Son and 6 more

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Byeonggeol MunDepartment of Chemical and Biomolecular Engineering, College of Engineering, Yonsei University, Seoul, Republic of Korea.ORCID https://orcid.org/0009-0009-8191-5766
Jinyoung KimBionanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea.ORCID https://orcid.org/0000-0002-7204-8527
Chang Gon KimDivision of Medical Oncology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-4929-8501
Seokhyeong GoDivision of Medical Oncology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Mina HanDivision of Medical Oncology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Yujin OuckDepartment of Chemical and Biomolecular Engineering, College of Engineering, Yonsei University, Seoul, Republic of Korea.
Soojin JangBionanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea.
Seong Uk SonBionanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea.
Gamin KimDivision of Medical Oncology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0001-8504-7921
Wonrak SonDivision of Medical Oncology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Eunjung KimDepartment of Bioengineering and Nano-Bioengineering, Research Center for Bio Materials and Process Development, Incheon National University, Incheon, Republic of Korea.ORCID https://orcid.org/0000-0001-9579-9414
Min Hee HongDivision of Medical Oncology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0003-3490-2195
Ja Hyun YeoDivision of Medical Oncology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Eun-Kyung LimBionanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea.ORCID https://orcid.org/0000-0003-2793-3700
Hye Ryun KimDivision of Medical Oncology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-1842-9070
Seungjoo HaamDepartment of Chemical and Biomolecular Engineering, College of Engineering, Yonsei University, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-4990-0523

Funding

a collaborative research project between Yonsei University College of Medicine and Dentistry, and Yonsei University College of Engineering 6-2026-0055Korea Medical Institute research program KMI20250215KRIBB Research Initiative Program KGM1032511KRIBB Research Initiative Program KGM1322511Ministry of Education RS-2024-00448784Ministry of Education RS-2024-00449792Ministry of Education RS-2024-00452599Ministry of Food and Drug SafetyMinistry of Health and Welfare RS-2022-CC125144Ministry of Health and Welfare RS-2024-00405569Ministry of Health and Welfare RS-2025-02213315Ministry of Science and ICT (MSIT) RS-2023-00261820Ministry of Science and ICT (MSIT) RS-2024-00348654Ministry of Science and ICT (MSIT) RS-2024-00459749Ministry of Science and ICT (MSIT) RS-2025-00554718Ministry of Science and ICT (MSIT) RS-2025-02214844Ministry of Science and ICT (MSIT) RS-2025-18362970Ministry of Science and ICT (MSIT) RS-2026-25481453Ministry of Trade, Industry and Energy RS-2024-00403563Ministry of Trade, Industry and Energy RS-2026-25538287the College of Medicine, College of Dentistry and the Institute of Engineering Research, Yonsei UniversityYonsei University College of Medicine 4-2023-1187Yonsei University College of Medicine 6-2023-0136Yonsei University College of Medicine C-2024-0024
6 · The paper itself

Abstract

Programmed death-ligand 1 (PD-L1) blockade improves outcomes in patients with various malignancies; however, biomarkers for monitoring treatment responses are lacking. This study presents a surface-enhanced Raman scattering (SERS)-based platform for the ultrasensitive detection of PD-L1 on circulating epithelial cell adhesion molecule-positive (EpCAM

Indexed as

EpCAM‐positive extracellular vesicleshead and neck squamous cell carcinomasimmune checkpoint blockadesliquid biopsiesnon‐small‐cell lung cancersprogrammed death‐ligand 1surface‐enhanced Raman scattering

Identifiers

PMID42397059
PMCPMC13334590

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.