Evidence map›Paper›PMID 42397627›Full record

SynthesisSleep & breathing = Schlaf & Atmung2026

Which nocturnal hypoxemia parameters are associated with ambulatory blood pressure monitoring in adults with obstructive sleep apnea? A systematic review.

Cíntia Felicio Adriano Rosa, Carolina Ferraz de Paula Soares, Michel Burihan Cahali

Abstract readSystematic Review
In one paragraph

Synthesis in Sleep & breathing = Schlaf & Atmung, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Cíntia Felicio Adriano RosaDepartment of Otolaryngology. Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brazil. dracintiarosa@usp.br.ORCID http://orcid.org/0000-0002-4885-5775
Carolina Ferraz de Paula SoaresMedical School, Faculdade Assis Gurgacz, Cascavel, Brazil.ORCID http://orcid.org/0000-0002-4740-1528
Michel Burihan CahaliDepartment of Otolaryngology. Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brazil.ORCID http://orcid.org/0000-0002-5704-160X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveSystemic arterial hypertension affects up to 50% of patients with obstructive sleep apnea (OSA) and represents one of the main modifiable cardiovascular risk factors. Hypoxemia is a recognized marker of OSA severity; however, it remains unclear which specific desaturation parameters during sleep, such as oxygen desaturation index (ODI), mean and minimum oxygen saturation (SpO

methodsA literature search was performed in PubMed, Web of Science, Scopus and Embase databases, covering all records available up to June 2025.

resultsA total of 5,587 records were identified through database searches, and 24 studies met the inclusion criteria. The studies revealed heterogeneous results, with some showing significant associations between hypoxemia indices and hypertension, while others did not. Evidence suggests that ODI3% is commonly related to increased BP, whereas minimum SpO

conclusionODI3% showed the most consistent association with increased BP across studies, whereas other hypoxemia indices yielded more variable results. Evidence regarding HB remains preliminary and warrants further investigation. These findings suggest that although ODI currently appears to be the most reliable marker, evidence from a single study indicates that composite indices such as HB may represent more informative predictors of BP outcomes and deserve further investigation in future studies.

Indexed as

Blood Pressure Monitoring, AmbulatoryHypertensionHypoxiaSleep Apnea, ObstructiveAdultHumansOxygen SaturationHypertensionHypoxic burdenNocturnal hypoxemiaObstructive sleep apneaOxygen desaturation index

Identifiers

PMID42397627
PMCPMC13331944

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.