Evidence map›Paper›PMID 42399446›Full record

ReviewEuropean journal of pediatrics2026

Consensus statement on the use of standardized early mobilization in pediatric patients admitted to pediatric intensive care units in Italy.

Matteo Di Nardo, Elisa Poletto, Ezio Bonanomi, Riccardo Carbonetti, Alessandra Conio, Elena Zardi, Silvana Massa, Giuseppe Pagano, Stefania Ferrario, Paolo Finazzi and 19 more

Abstract readConsensus StatementReview
PubMed Publisher
In one paragraph

Review in European journal of pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

Matteo Di NardoPediatric Intensive Care Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy. matteo.dinardo@opbg.net.
Elisa PolettoPediatric Intensive Care Unit, San Bortolo Hospital, Vicenza, Italy.
Ezio BonanomiPediatric Anesthesia and Intensive Care Unit, Papa Giovanni XXIII Hospital, Bergamo, Italy.
Riccardo CarbonettiNeurofunctional Rehabilitation Unit, Clinical Area of Neuroscience and Neurorehabilitation, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Alessandra ConioPediatric Intensive Care Unit, Anesthesia, Resuscitation, and Emergency Department, University of Turin, Turin, Italy.
Elena ZardiPhysical Medicine and Rehabilitation Unit, Department of Continuity of Care and Disability, IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Bologna, Italy.
Silvana MassaPhysical Medicine and Rehabilitation Unit, Department of Continuity of Care and Disability, IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Bologna, Italy.
Giuseppe PaganoPediatric Intensive Care Unit, University Hospital, Verona, Italy.
Stefania FerrarioPediatric Intensive Care Unit, Department of Pediatric Anesthesia and Intensive Care, "Vittore Buzzi" Children's Hospital, Milan, Italy.
Paolo FinazziUnit of Pediatric Anesthesia and Intensive Care, Ospedale Dei Bambini-ASST Spedali Civili, Brescia, Italy.
Alberto GianniniUnit of Pediatric Anesthesia and Intensive Care, Ospedale Dei Bambini-ASST Spedali Civili, Brescia, Italy.
Angela AmigoniPaediatric Intensive Care Unit, Department of Woman's and Child's Health, University of Padua, Padua, Italy.
Raffaella SagrediniInstitute for Maternal and Child Health-IRCCS, "Burlo Garofalo", Trieste, Italy.
Giacomo PaluzzanoInstitute for Maternal and Child Health-IRCCS, "Burlo Garofalo", Trieste, Italy.
Nicola ReiaInstitute for Maternal and Child Health-IRCCS, "Burlo Garofalo", Trieste, Italy.
Roberta PallottoDepartment of Pediatric Anaesthesia and Intensive Care, S.C. SOD Anestesia E Rianimazione Pediatrica, Ospedale G. Salesi, Ancona, Italy.
Veronica RecchiutiNeurofunctional Rehabilitation Unit, Clinical Area of Neuroscience and Neurorehabilitation, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Elisabetta LampugnaniPediatric Anaesthesia and Intensive Care Unit, AOU SS. Antonio E Biagio E Cesare Arrigo IT, Alessandria, Italy.
Geremia Zito MarinosciPediatric Intensive Care Unit, Santobono Children's Hospital, Naples, Italy.
Manuela L'ErarioPediatric Intensive Care Unit, Meyer Children's Hospital, IRCCS, Florence, Italy.
Paola MoliterniPediatric Intensive Care Unit, Pope Giovanni XIII Pediatric Hospital, Bari, Italy.
Riccardo RicciProfessional Development, Continuing Education and Nursing Research Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Lazio, Italy.
Marcello PiazzaPediatric Intensive Care Unit, ARNAS Civico, Palermo, Italy.
Stefania BianzinaNeonatal and Pediatric Intensive Care Unit, Emergency Department, IRCCS Istituto Giannina Gaslini, Genoa, Italy.
Giulia GorghelliRehabilitation Unit, Papa Giovanni XXIII Hospital, Bergamo, Italy.
Sara SchirruSSD Servizio Di Cardioanestesia E Rianimazione Dell'età Neonatale, Pediatrica E del Congenito Adulto, IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Bologna, Italy.
Manuela MoncadaScientific Directorate, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Maria Cristina MondardiniPediatric Anesthesia and Intensive Care Unit, Women's and Children's Department, IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Bologna, Italy.
Italian Society of Neonatal, Pediatric Anesthesia, Intensive Care (SARNePI)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prolonged immobility contributes to pediatric intensive care unit (PICU)-acquired weakness and postintensive care syndrome (PICS). Early mobilization (EM) shows feasibility and potential benefits in adults, and pediatric experiences suggest safety, though data are limited and practice varies. There is a wide variability in Italy regarding EM practices. Thus, we aimed to develop consensus statements to standardize EM across Italian PICUs today while respecting local variability. This project was conducted by a 20-member multidisciplinary panel of Italian PICU experts, including nurses and physiotherapists. The project was endorsed by the Italian Society of Neonatal and Pediatric Anesthesia and Intensive Care (SARNePI). A comprehensive search (2010-2015 July 2025) in PubMed, CINAHL, and PEDro was conducted. Eligible studies included prospective and retrospective studies, systematic reviews, meta-analyses, and guidelines. Nine EM research areas were defined; Statements were drafted using a Quaker-based consensus methodology and voted using the RAND/UCLA appropriateness method. From 8380 records, 113 studies met eligibility. Twenty-two statements and four tables were drafted; 20 statements and three tables achieved strong agreement in the first round. The remaining two statements and one table were revised and were classified with weak agreement. Attendance was 93% at online meetings.

conclusionThis EM consensus provides standardized, implementable statements to guide EM adoption across Italian PICUs while accommodating local practice differences; future work should focus on validation, implementation, and dissemination. WHAT IS KNOWN: • Prolonged immobility in the PICU is one of the modifiable factors associated with PICU-acquired weakness, delirium, and post-intensive care syndrome. • In Italy only 15% of patients admitted to PICU receives Early Mobilization practices with great variability across PICUs. WHAT IS NEW: • 22 pragmatic statements and four tables have been developed to promote standardized EM interventions across Italian PICUs, while accounting for variability of practices and equipment. • The provision of graded Early Mobilization, responsive to the child's condition and severity of illness, may promote functional recovery both during and beyond the PICU stay.

Indexed as

Early AmbulationIntensive Care Units, PediatricChildChild, PreschoolCritical IllnessHumansItalyPediatric early mobilizationPediatric rehabilitationPICSPICU-acquired syndrome

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.