In one paragraphArticle in Gut microbes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
7 authors.
Sweta GhoshDepartment of Microbiology and Immunology, Brown Cancer Center, Center for Microbiomics, Inflammation and Pathogenicity, Center for Integrative Environmental Health Sciences, University of Louisville, Louisville, KY, USA.ORCID 0000-0003-0613-8687 Zachary Matthew VanwinkleDepartment of Microbiology and Immunology, Brown Cancer Center, Center for Microbiomics, Inflammation and Pathogenicity, Center for Integrative Environmental Health Sciences, University of Louisville, Louisville, KY, USA.
Kanchan Sinha RoyDepartment of Microbiology and Immunology, Brown Cancer Center, Center for Microbiomics, Inflammation and Pathogenicity, Center for Integrative Environmental Health Sciences, University of Louisville, Louisville, KY, USA.ORCID 0000-0001-7726-6788 Miroslav StýbloDepartment of Nutrition, CB# 7461, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Mayukh BanerjeeDepartment of Pharmacology and Toxicology, University of Louisville School of Medicine, Louisville, KY, USA.
James CollinsDepartment of Microbiology and Immunology, Center for Microbiomics, Inflammation and Pathogenicity, University of Louisville, Louisville, KY, USA.ORCID 0000-0003-2479-5189 Venkatakrishna Rao JalaDepartment of Microbiology and Immunology, Brown Cancer Center, Center for Microbiomics, Inflammation and Pathogenicity, Center for Integrative Environmental Health Sciences, University of Louisville, Louisville, KY, USA.ORCID 0000-0002-4206-7305 Funding
Understanding the Host-Microbiome-Therapeutic Triad: Implications for Designing Alternative IntravaginalP20GM125504 · NIGMS · UNIVERSITY OF LOUISVILLE · PI Shirin Ghods · 2018 to 2026
$24.4MUniversity of Louisville Center for Integrative Environmental Health SciencesP30ES030283 · NIEHS · UNIVERSITY OF LOUISVILLE · PI Amanda Jo LeBlanc · 2020 to 2026
$10.0MAHR-NLRP6 interactions in gut barrier dysfunction and colitisR01DK135603 · NIDDK · UNIVERSITY OF LOUISVILLE · PI Venkatakrishna Rao Jala · 2024 to 2026
$1.6MNIDDK NIH HHS R01 DK135603NIEHS NIH HHS P30 ES030283NIGMS NIH HHS P20 GM125504
6 · The paper itselfAbstract
Chronic exposure to inorganic arsenic (iAs) remains a major environmental health concern and is associated with significant gastrointestinal (GI) disorders, including gastroenteritis, diarrhea, and inflammatory bowel disease-like symptoms. Gut microbiota plays a critical role in mitigating arsenic toxicity, as germ-free or antibiotic-treated mice exhibit reduced fecal arsenic excretion and greater tissue accumulation. We previously showed that the microbial metabolite Urolithin A (UroA) protects against iAs-induced cytotoxicity, apoptosis, oxidative stress, and ROS production in vitro. In this study, using humanized
Indexed as
ArsenicCoumarinsGastrointestinal MicrobiomeMethyltransferasesProtective AgentsAnimalsBacteriaColonCytokinesHumansIntestinal Barrier FunctionIntestinal MucosaMiceMice, TransgenicTight Junction Proteins3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-oneArsenicCoumarinsCytokinesMethyltransferasesProtective AgentsTight Junction Proteinsgut barrier dysfunctionGut microbiotahAS3MT transgenic miceinorganic arsenic (iAs)intestinal inflammationUrolithin A (UroA)
Identifiers
PMID42400257
PMCPMC13348994
What Socratic holds
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