Evidence map›Paper›PMID 42400276›Full record

Observational studyTherapeutic advances in respiratory disease

Evaluating current bronchiectasis care in Italy according to the 2025 European respiratory society recommendations.

Alessandro De Angelis, Vittoria Comellini, Andrea Gramegna, Salvatore Battaglia, Giuliano Montemurro, Angela Bellofiore, Francesco Pagnini, Emilia Privitera, Margherita Ori, Edoardo Simonetta and 5 more

Abstract readObservational StudyMulticenter Study
In one paragraph

Observational study in Therapeutic advances in respiratory disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Alessandro De AngelisDepartment of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.ORCID 0009-0004-3544-0361
Vittoria ComelliniRespiratory and Critical Care Unit, IRCCS Sant'Orsola Malpighi Hospital, Bologna, Italy.
Andrea GramegnaDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.
Salvatore BattagliaDepartment of Health Promotion Sciences Maternal and Infantile Care, Internal Medicine and Medical Specialties (ProMISE), University of Palermo, Palermo, Italy.ORCID 0000-0002-2867-917X
Giuliano MontemurroUOC Pneumologia, Dipartimento Scienze Mediche e Chirurgiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Angela BellofioreInternal Medicine Department, Respiratory and Cystic Fibrosis Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, Milan, Italy.
Francesco PagniniDepartment of Psychology, Università Cattolica del Sacro Cuore, Milan, Italy.
Emilia PriviteraDepartment of Healthcare Professions, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Margherita OriInternal Medicine Department, Respiratory and Cystic Fibrosis Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, Milan, Italy.
Edoardo SimonettaIRCCS Humanitas Research Hospital, Respiratory Unit, Rozzano, Milan, Italy.
Mattia NigroDepartment of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.ORCID 0000-0003-4735-823X
James D ChalmersDivision of Respiratory Medicine and Gastroenterology, University of Dundee, Dundee, UK.
Donatella NobileAssociazione Italiana Bronchiettasie, Milan, Italy.
Francesco BlasiDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.
Stefano AlibertiDepartment of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, Milan 20072, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNational quality standards for bronchiectasis in Italy were last defined in 2016. The publication of the 2025 European Respiratory Society (ERS) guidelines offers the opportunity to evaluate current clinical practice against updated evidence-based recommendations.

objectivesTo assess the extent to which Italian bronchiectasis centers align with key statements from the 2025 ERS guidelines.

designNational, multicenter, cross-sectional observational study based on a structured survey of Italian bronchiectasis centers, aligned with the 2025 ERS recommendations.

methodsA national survey was conducted across Italian bronchiectasis centers affiliated with the Italian Bronchiectasis Patient Association (AIB). The structured questionnaire assessed center organization, diagnostic resources, multidisciplinary care, and alignment with ten predefined core management domains derived from the 2025 ERS recommendations.

resultsMost centers reported universal access to minimum bundle etiological tests, with improved capacity compared with 2016. However, specialized diagnostics for rare causes, structured physiotherapy programs, and written self-management plans remain inconsistently available. Long-term inhaled antibiotics and macrolides were widely prescribed, though access barriers persist. Monitoring practices were heterogeneous.

conclusionDespite clear progress, substantial variability persists in physiotherapy access, rare disease diagnostics, self-management tools, and routine monitoring. Updated Italian quality standards aligned with ERS 2025 principles are warranted.

Indexed as

BronchiectasisGuideline AdherencePractice Guidelines as TopicPractice Patterns, Physicians'Quality Indicators, Health CareAnti-Bacterial AgentsCross-Sectional StudiesHealth Care SurveysHealth Services AccessibilityHumansItalyPhysical Therapy ModalitiesSocieties, MedicalSurveys and QuestionnairesAnti-Bacterial Agentsbronchiectasisclinical networkshealthcare organizationstandard operating procedures

Identifiers

PMID42400276
PMCPMC13333048

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.