Evidence map›Paper›PMID 42401903›Full record

ArticleJournal of nanobiotechnology2026

Enzyme-enhanced albumin-stabilized nanopolymers for cascade catalysis-driven ferroptosis-immunotherapy.

Peng Yu, Shuchun Yu, Xiaoping Yin, Zihao Zhou, Yixuan Chen, Xuehong Zheng, Jitao Ling, Panpan Xia, Yuhong Dai, Weiwei Zeng and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nanobiotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Peng Yu *Department of Endocrinology and Metabolism, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, China.
Shuchun Yu *Department of Anesthesiology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, China.
Xiaoping YinJiujiang Clinical Precision Medicine Research Center, Jiujiang, 332005, China.
Zihao ZhouXiangya School of Pharmaceutical Sciences, Central South University, Changsha, 410013, China.
Yixuan ChenDepartment of Anesthesiology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, China.
Xuehong ZhengDepartment of Endocrinology and Metabolism, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, China.
Jitao LingDepartment of Endocrinology and Metabolism, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, China.
Panpan XiaDepartment of Endocrinology and Metabolism, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, China.
Yuhong DaiDepartment of Endocrinology and Metabolism, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, China.
Weiwei ZengXiangya School of Pharmaceutical Sciences, Central South University, Changsha, 410013, China. 225103@csu.edu.cn.
Jing ZhangDepartment of Anesthesiology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, China. zhangjing666doc@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ferroptosis, an iron-dependent form of programmed cell death, holds significant promise for cancer therapy due to its unique redox-driven mechanism and immunogenic potential. However, its therapeutic efficacy is often compromised by inadequate catalytic kinetics and an unfavorable tumor microenvironment. Here, we develop a multifunctional nanocatalyst (BCuP@G) based on albumin-stabilized polypyrrole doped with multivalent Cu ions and conjugated with glucose oxidase (GOx) to enable enzyme-enhanced cascade catalysis for ferroptosis-immunotherapy. The embedded Cu

Indexed as

AlbuminsFerroptosisGlucose OxidaseImmunotherapyNanoparticlesPolymersAnimalsCatalysisCell Line, TumorCopperHumansMiceOxidation-ReductionPyrrolesAlbuminsCopperGlucose OxidasePolymerspolypyrrolePyrrolesAlbumin-stabilized nanoploymersCascade catalysisFerroptosisGlucose oxidaseImmunotherapy

Identifiers

PMID42401903
PMCPMC13613808

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.