ArticleThe ISME journal2026
Photosynthesis-driven interactions in the phycosphere enhance bacterial extracellular superoxide production.
Article in The ISME journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Extracellular superoxide generated by heterotrophic bacteria influences aquatic redox transformations, yet its regulation within the phycosphere remains poorly understood. Here, we show that the cyanobacterium Microcystis aeruginosa enhances extracellular superoxide production by Pseudomonas sp. QJX-1 under illumination. Cocultivation increased extracellular superoxide production approximately three-fold over bacterial monoculture, with maximum enhancement during carbon starvation. Membrane separation localized detectable superoxide production to the bacterial chamber, indicating that diffusible algal products stimulated bacterial superoxide production. Mechanistically, illuminated cocultures showed 20.4% higher photocurrent than algal monocultures and accumulated the highest extracellular NADP(H) levels, indicating intensified photosynthesis-associated extracellular redox activity. Reduced nicotinamide cofactors stimulated diphenyleneiodonium-sensitive QJX-1-associated superoxide production, consistent with an oxidoreductase-associated route for one-electron reduction of molecular oxygen. In parallel, coculture accumulated catecholate siderophores, consistent with intensified microscale Fe competition; this siderophore-enhanced response required metabolically active bacterial cells and was attenuated by respiratory-chain inhibition. Representative extracellular redox-active and algal photoactive components further enhanced the bacterial response, with cytochrome c and chlorophyll a stimulating QJX-1-associated superoxide production under defined conditions. Functionally, during the carbon-starvation interval coinciding with peak superoxide production, the apparent sulfamethoxazole removal rate constant in coculture was 2.6 times that observed for QJX-1 alone. Moreover, quenching extracellular reactive oxygen species (ROS) impaired metabolic activity under diverse chemical stressors and reduced carbon, nitrogen, and phosphorus substrate utilization. Collectively, these findings identify photosynthesis-dependent phycosphere interactions as regulators of bacterial superoxide production, linking biogenic ROS to contaminant transformation, chemical-stress resilience, and elemental nutrient turnover.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.