ArticleClinical oral implants research2026
Effect of Medication Intake on Dental Implant-Related Outcomes-A Scoping Review.
Article in Clinical oral implants research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe objective of this scoping review was to evaluate the effect of systemic medications on dental implant outcomes in medically compromised patients. MATERIAL AND
methodsElectronic and manual searches were conducted for this scoping review. Clinical studies reporting on systemic medication intake and implant outcomes were eligible. Studies reporting on the use of antiresorptive medications were not included in this scoping review. Qualitative evaluation was performed as meta-analysis was not feasible due to study heterogeneity.
resultsOverall, 51 studies met the inclusion criteria and were eligible for assessment. Six medications were identified to potentially impact the short- and long-term implant outcomes. In total, 8 studies reported the intake of anti-hypertensives (AHTNs), 9 studies reported the intake of anticoagulants (ACs), 12 studies reported the intake of immunosuppressants (IMNs), 11 studies reported the intake of nonsteroidal anti-inflammatories (NSAIDs), 12 studies reported the intake of proton-pump inhibitors (PPIs), and 12 studies reported the intake of selective serotonin reuptake inhibitors (SSRIs). Moreover, 1 study reported pooled data regarding the use of PPIs, SSRIs, AHTNs, and statins. From these, the following results were drawn: ACs, long-term NSAID use, prolonged use of PPIs, and SSRIs are associated with increased risk of implant failure and/or marginal bone loss. Additionally, AHTNs and IMNs have no effect on implant-related outcomes. Medication-related biological implant complications are underreported in the literature.
conclusionMedication intake can significantly influence implant-related outcomes.
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