Evidence map›Paper›PMID 42403074›Full record

ArticleAmerican journal of hematology2026

EIF2AK1 As a Key Genetic Determinant of Luspatercept Resistance in Transfusion-Dependent Thalassemia.

Anthony Iscaro, Simona Leoni, Filippo Russo, Valentina Brancaleoni, Barbara Eleni Rosato, Roberta Marra, Antonella Nostroso, Natalia Scaramellini, Daniele Lello Panzieri, Iris Villa and 9 more

Abstract readLetter
In one paragraph

Article in American journal of hematology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Anthony IscaroDipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, Naples, Italy.ORCID https://orcid.org/0009-0008-4118-7007
Simona LeoniDipartimento di Scienze Cliniche e di Comunità, Dipartimento di Eccellenza 2023-2027, University of Milan, Milan, Italy.ORCID https://orcid.org/0009-0001-4178-4732
Filippo RussoDipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, Naples, Italy.ORCID https://orcid.org/0000-0001-8128-9878
Valentina BrancaleoniSC Medicina ad Indirizzo Metabolico, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Barbara Eleni RosatoDipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, Naples, Italy.
Roberta MarraDipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, Naples, Italy.
Antonella NostrosoDipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, Naples, Italy.ORCID https://orcid.org/0009-0007-3419-1641
Natalia ScaramelliniDipartimento di Scienze Cliniche e di Comunità, Dipartimento di Eccellenza 2023-2027, University of Milan, Milan, Italy.ORCID https://orcid.org/0000-0002-5509-3107
Daniele Lello PanzieriSC Medicina ad Indirizzo Metabolico, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.ORCID https://orcid.org/0000-0003-2578-3550
Iris VillaUniversity of Milan, Milan, Italy.
Teresa CeglieDepartment of Clinical and Biological Sciences, University of Turin, Turin, Italy.
Carmen Maria GagliotiDepartment of Clinical and Biological Sciences, University of Turin, Turin, Italy.
Neha KargutkarDepartment of Clinical and Biological Sciences, University of Turin, Turin, Italy.
Vito Alessandro LasorsaCEINGE Biotecnologie Avanzate Franco Salvatore, Naples, Italy.
Mario CapassoDipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, Naples, Italy.ORCID https://orcid.org/0000-0003-3306-1259
Giovanni Battista FerreroDepartment of Clinical and Biological Sciences, University of Turin, Turin, Italy.ORCID https://orcid.org/0000-0002-3793-5788
Immacolata AndolfoDipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, Naples, Italy.ORCID https://orcid.org/0000-0003-0493-812X
Irene MottaDipartimento di Scienze Cliniche e di Comunità, Dipartimento di Eccellenza 2023-2027, University of Milan, Milan, Italy.ORCID https://orcid.org/0000-0001-5701-599X
Roberta RussoDipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, Naples, Italy.ORCID https://orcid.org/0000-0002-3624-7721

Funding

Ministero dell'Università e della Ricerca PRIN2022(2022L5YWZT)
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID42403074
PMCPMC13428372

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.