ArticleAmerican journal of preventive cardiology2026
Rationale and design of Dongzong CArdIovascuLar Bio-imaging RegistrY (DAILY) study: Bridging multiomics, imaging and cardiovascular disease.
Article in American journal of preventive cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06894095 (Dongzong Cardiovascular Bio-imaging Registry Study), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Dongzong Cardiovascular Bio-imaging Registry Study
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Abstract
Background: Cardiovascular disease (CVD) remains the leading cause of global mortality, necessitating a large-scale bioimaging database to advance personalized precision medicine strategies. Objectives: The Dongzong Cardiovascular Bio-imaging Registry (DAILY) study was designed to establish a large-scale Chinese cardiovascular bioimaging database (NCT06894095). It aims to address ethnic disparities in genetics and imaging, and to elucidate crucial driving mechanisms and effects of genetic biology and exposure factors on imaging-derived intermediate phenotypes and CVD. Methods: This prospective, multicenter study plans to enroll 50,000 adults from six medical centers across China. It employs a comprehensive data framework, systematically collecting information on exposure factors, high-throughput multiomics (blood and saliva samples), and cardiopulmonary computed tomography (CT) imaging (chest CT, cardiac CT) for cardiac, coronary and pulmonary phenotypes assessment. The primary outcome is a composite major adverse cardiovascular event, including all-cause death, nonfatal myocardial infarction, and nonfatal stroke. Results: To September 10, 2025, the study has recruited 8699 participants in Nanjing, China. Standardized biospecimen collection was performed, obtaining blood samples from 8632 participants and saliva specimens from 8621 individuals, and cardiopulmonary CT scans have been completed in 8699 participants. The cohort maintains a 1-year follow-up rate of 98.9%. Conclusions: The DAILY study will deepen our understanding of ethnic disparities in CVD, help elucidate the effects of genetic and exposure factors on cardiopulmonary intermediate phenotypes, and decipher the pathophysiological mechanisms underlying CVD.
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