ArticleAmerican journal of preventive cardiology2026
Age and sex specific coronary plaque characteristics among South Asians: Insights from the DILWALE CTA study.
Article in American journal of preventive cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: South Asians (SA) face disproportionately high rates of premature coronary artery disease (CAD), often underestimated by traditional risk calculators. We aim to characterize CT angiography (CTA)-derived plaque composition, plaque burden, and association with risk factors among SA in the DILWALE registry. Methods: Clinically indicated coronary CTAs from 341 patients in the Baylor Scott and White DILWALE registry were analyzed using Artificial intelligence enabled quantitative coronary plaque analysis (AIQCPA) to characterize age- and sex-specific plaque burden. Results: Of 341 patients, 63% ( Conclusion: This study represents one of the largest CTA based cohorts evaluating plaque characteristics in SA in the United States. Our findings highlight the value of AIQCPA CTA in revealing subclinical plaque, particularly non-calcified plaque in SA. Future studies should identify optimal imaging strategies for SA along with outcome-based validation of plaque characteristics.
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