ArticleOpen forum infectious diseases2026
Long-Term Follow-Up of Patients With Classic Fever of Unknown Origin: Prognostic Outcomes and Management Strategies.
Article in Open forum infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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7 authors.
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Abstract
Background: This study evaluates the long-term prognosis of patients with classic fever of unknown origin (FUO) who are discharged without a definitive diagnosis, enhances the understanding of FUO, and provides evidence-based guidance for its diagnosis and management. Method: A retrospective analysis was conducted on hospitalized patients at the Department of Infectious Diseases, Peking Union Medical College Hospital, who met the diagnostic criteria for classic FUO. Clinical characteristics and diagnostic outcomes were summarized, and patients without a definitive diagnosis (including those classified as clinical and indeterminate diagnoses) were examined longitudinally to determine their prognostic outcomes. Results: Overall, 739 patients with classic FUO were included. At discharge, 36.8% ( Conclusions: Most patients with classic FUO without a definitive diagnosis have a favorable prognosis, suggesting avoiding overtreatment. This study underscores the value of diagnostic therapies and close follow-up as key strategies in clinical management.
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