ArticleFrontiers in aging neuroscience2026
Ershiwuwei Shanhu Pill ameliorates cognitive impairment in Alzheimer's disease mice by remodeling gut microbiota and host serum metabolites.
Article in Frontiers in aging neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Alzheimer's disease (AD), with the most prominent pathological feature of the accumulation of amyloid-beta (Aβ) plaques and neurofibrillary tangles of hyperphosphorylated tau proteins (P-tau), is the foremost cause of dementia. Ershiwuwei Shanhu Pill (ESP) is commonly used in clinical practice in Tibetan areas to treat AD, and has been shown to alleviate cognitive impairment. However, whether ESP exerts its therapeutic effects by modulating the gut microbiota and serum metabolites remains unclear. In this study, APPswe/PSEN1dE9 transgenic (APP/PS1) mice (
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