Bioinspired Ruthenium Arene Complex with Pseudo-Vacant Coordination Sites as Efficient Small-Molecular Antioxidant Enzyme Mimics for Preventing Vascular Restenosis.

Haojie Xu, Yichen Cai, Wei Geng, Zhenyu Xing, Jiayan Zheng, Xiaolin Wang, Yang Gao, Qiu Chen, Li Qiu, Chong Cheng

Abstract read

In one paragraph

Article in Research (Washington, D.C.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Haojie XuDepartment of Medical Ultrasound, West China Hospital, Sichuan University, Chengdu 610041, China.

Yichen CaiDepartment of Endocrinology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610072, China.

Wei GengCollege of Polymer Science and Engineering, State Key Laboratory of Advanced Polymer Materials, Sichuan University, Chengdu 610065, China.

Zhenyu XingCollege of Polymer Science and Engineering, State Key Laboratory of Advanced Polymer Materials, Sichuan University, Chengdu 610065, China.

Jiayan ZhengDepartment of Endodontics, Department of Orthodontics, State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.

Xiaolin WangSchool of Pharmacy and State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macao 999078 China.

Yang GaoDepartment of Medical Ultrasound, West China Hospital, Sichuan University, Chengdu 610041, China.

Qiu ChenDepartment of Endocrinology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610072, China.

Li QiuDepartment of Medical Ultrasound, West China Hospital, Sichuan University, Chengdu 610041, China.

Chong ChengCollege of Polymer Science and Engineering, State Key Laboratory of Advanced Polymer Materials, Sichuan University, Chengdu 610065, China.ORCID https://orcid.org/0000-0002-6872-2240

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the ongoing progress in coronary interventional therapy, the progression of atherosclerosis is no longer solely governed by its natural course. Postprocedural neointimal hyperplasia and plaque formation markedly increase the risk of cardiovascular events, where chronic, unresolved inflammation and the overproduction of reactive oxygen species (ROS) play a critical role in driving plaque development. Drawing inspiration from the reaction mechanisms of intracellular antioxidant defense systems, we report the de novo design of a ruthenium arene complex (RuC

Identifiers

PMID42404352

DOI10.34133/research.1353

PMCPMC13329158

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.