A recombinant humanized type III collagen coating with anti-inflammatory and endothelialization-promoting effects for left atrial appendage closure devices.

Yihang Zhou, Jiaqi Wang, Longjian Zhang, Li Yang, Yunbing Wang

Abstract read

In one paragraph

Article in Regenerative biomaterials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yihang ZhouNational Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University, Chengdu 610065, China.

Jiaqi WangNational Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University, Chengdu 610065, China.

Longjian ZhangNational Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University, Chengdu 610065, China.

Li YangNational Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University, Chengdu 610065, China.

Yunbing WangNational Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University, Chengdu 610065, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcatheter cardiac occluders represent a mainstay of minimally invasive therapy for congenital heart disease and for the prevention of left atrial appendage-related thrombosis. However, their long-term clinical efficacy is constrained by frequent post-implant complications, including device-related thrombosis, persistent inflammation, incomplete reendothelialization, and delayed tissue healing. Herein, we developed a hierarchical functional modification strategy for biodegradable polymers via stable covalent grafting of recombinant humanized type III collagen (rhCol III)-a biomaterial with robust cell adhesiveness and low immunogenicity-onto the polymer surface. Systematic

Indexed as

anti-inflammatoryleft atrial appendage occluderrecombinant humanized collagen type IIIreendothelialization

Identifiers

PMID42404409

DOI10.1093/rb/rbag114

PMCPMC13332433

What Socratic holds

Textmetadata

LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.