Evidence map›Paper›PMID 42405079›Full record

ArticleRSC advances2026

Apt19s-functionalized 3D-printed PCL/58S bioactive glass scaffolds

Samira Karimian, Ghasem Dini, Negar Nasri, Fereshteh Mahmoodiyan Najafabadi, Shaghayegh Saharkhiz

Abstract read
In one paragraph

Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Samira KarimianDepartment of Nanotechnology, Faculty of Chemistry, University of Isfahan Isfahan 81746-73441 Iran g.dini@sci.ui.ac.ir.
Ghasem DiniDepartment of Nanotechnology, Faculty of Chemistry, University of Isfahan Isfahan 81746-73441 Iran g.dini@sci.ui.ac.ir.ORCID https://orcid.org/0000-0002-0405-8424
Negar NasriDepartment of Biotechnology, Faculty of Biological Science and Technology, University of Isfahan Isfahan 81746-73441 Iran.ORCID https://orcid.org/0000-0003-2845-6424
Fereshteh Mahmoodiyan NajafabadiDepartment of Nanotechnology, Faculty of Chemistry, University of Isfahan Isfahan 81746-73441 Iran g.dini@sci.ui.ac.ir.
Shaghayegh SaharkhizDepartment of Biotechnology, Faculty of Biological Science and Technology, University of Isfahan Isfahan 81746-73441 Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study presents a novel aptamer-functionalized 3D-printed scaffold designed to promote adhesion and osteogenic differentiation of human bone marrow-derived mesenchymal stem cells (hBMSCs). Composite scaffolds consisting of 55 wt% polycaprolactone (PCL) and 45 wt% 58S bioactive glass (BG) were fabricated using fused deposition modeling (FDM). Surface biofunctionalization was achieved through thiol-maleimide click chemistry to covalently immobilize thiol-terminated Apt19s aptamer. Successful conjugation was confirmed by carbon quantum dot labeling and fluorescence microscopy.

Identifiers

PMID42405079
PMCPMC13330724

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.