Evidence map›Paper›PMID 42405295›Full record

ArticleACG case reports journal2026

Novel Endoscopic Closure of Iatrogenic Hypopharyngeal Perforations Using Through-the-Scope Tissue Approximation Clips.

Pranav Ramamurthy, Kais Zakharia

Abstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Pranav RamamurthyDepartment of Internal Medicine, University of Massachusetts Chan Medical School - Baystate Medical Center, Springfield, MA.ORCID https://orcid.org/0009-0009-5294-9991
Kais ZakhariaDivision of Gastroenterology, University of Massachusetts Chan Medical School - Baystate Medical Center, Springfield, MA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypopharyngeal perforation is a rare but potentially life-threatening complication of upper aerodigestive tract instrumentation. Management strategies remain controversial, and data supporting flexible endoscopic closure in this region are limited. We describe 3 cases of iatrogenic hypopharyngeal perforations successfully managed with MANTIS through-the-scope tissue approximation clips as part of a multidisciplinary approach. All defects were closed endoscopically. Two patients achieved complete mucosal healing without surgical intervention. One patient experienced clinical decline related to comorbid illness rather than closure failure. Endoscopic closure using through-the-scope clips may be a feasible option in carefully selected patients when performed early with multidisciplinary collaboration.

Indexed as

endoscopic closurehypopharyngeal perforationiatrogenic injurythrough-the-scope clipsupper esophageal sphincter

Identifiers

PMID42405295
PMCPMC13331407

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.