ArticleInvestigative and clinical urology2026
Outcomes after kidney transplantation in patients with urinary diversions or bladder augmentations: A 20-year nationwide study.
Article in Investigative and clinical urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposePatients with lower urinary tract diversions, either due to congenital malformations of the urinary tract and/or cancer, have a higher risk of chronic and end-stage kidney disease. Data on functional and surgical outcomes of kidney transplantation (KTx) in this patient population is limited. This study aims to evaluate post-transplant outcomes in patients with urinary diversions or bladder augmentations with over two decades of national data. MATERIALS AND
methodsThis is a retrospective, national cohort study of KTx recipients transplanted between year 2000-2021, with documented prior urinary diversions or bladder augmentations. Short- and long-term complications were assessed and graded using the Clavien-Dindo classification. Patient survival was analyzed using Kaplan-Meier estimates, and graft loss was evaluated using a competing risk time-dependent Cox regression model, with death as a competing event.
resultsTwenty-five patients were identified and included, categorized as follows: Ileal conduit or continent cutaneous urinary diversion (n=9), Mitrofanoff with bladder augmentation (n=8), Mitrofanoff without bladder augmentation (n=6), and isolated bladder augmentation (n=2). Median age at transplantation was 28 years (interquartile range, 18-40). Short-term complications included urinary tract infection (UTI) (n=10), peri-graft fluid collection (n=7), bleeding (n=6), sepsis (n=4), and ureteral obstruction (n=4). Long-term complications included recurrent UTIs (n=18), graft-related abscess/infection (n=11), hydronephrosis (n=6), and ileus (n=4). Twenty-six grafts were included in the survival analysis. Ten-year patient and graft survival were 91.7% and 85.5%, respectively.
conclusionsKTx in patients with urinary diversions is rare. This study carefully suggests that these patients can be considered as candidates for KTx.
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