Evidence map›Paper›PMID 42405988›Full record

ArticleInternational urology and nephrology2026

Association between 24-h proteinuria and phenotypic age acceleration in adults with preserved kidney function: a cross-sectional study.

Yiqi Su, Fangfang Xiang, Yi Fang, Xiaoqiang Ding, Wuhua Jiang

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Article in International urology and nephrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Yiqi Su *Department of Nephrology, Zhongshan Hospital, Fudan University, No 180 Fenglin Rd, Shanghai, China.
Fangfang Xiang *Department of Nephrology, Zhongshan Hospital, Fudan University, No 180 Fenglin Rd, Shanghai, China.
Yi FangDepartment of Nephrology, Zhongshan Hospital, Fudan University, No 180 Fenglin Rd, Shanghai, China. fang.yi@zs-hospital.sh.cn.
Xiaoqiang DingDepartment of Nephrology, Zhongshan Hospital, Fudan University, No 180 Fenglin Rd, Shanghai, China. ding.xiaoqiang@zs-hospital.sh.cn.
Wuhua JiangDepartment of Nephrology, Zhongshan Hospital, Fudan University, No 180 Fenglin Rd, Shanghai, China. jiangwuhua@msn.cn.ORCID https://orcid.org/0000-0001-8475-507X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePhenotypic age acceleration (PhenoAgeAccel) captures biological aging beyond chronological age and has been associated with adverse health outcomes. Proteinuria is a common manifestation of kidney injury, yet its relationship with biological aging acceleration in individuals with preserved kidney function remains unclear.

methodsWe conducted a cross-sectional study among adult nephrology outpatients with an estimated glomerular filtration rate (eGFR) > 60 mL/min/1.73 m

resultsAmong 253 adults with preserved eGFR (median age 44 years; median eGFR 93 mL/min/1.73 m

conclusionsElevated proteinuria is associated with accelerated biological aging in adults with preserved kidney function, highlighting a potential link between early kidney injury and accelerated biological aging.

Indexed as

Biological agingPhenotypic age accelerationPreserved kidney functionProteinuria

Identifiers

PMID42405988

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.