ReviewFish physiology and biochemistry2026
Mitochondrial regulation of brain development: evidence from zebrafish models.
Review in Fish physiology and biochemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mitochondria play a vital role in maintaining cellular energy balance, regulating apoptosis and controlling redox signaling during neurodevelopment. Disruption of these biological processes has emerged as a key mechanism underlying neurodevelopmental disorders and developmental neurotoxicity. Mitochondria influence neurodevelopmental phases, including neuronal proliferation and differentiation. The zebrafish serves as an exemplary model for examining the impact of mitochondria and energy metabolism on neurodevelopment, owing to its optical transparency, rapid embryonic development, and suitability for genetic manipulation. In this review, we summarize current knowledge on how mitochondrial processes direct brain development in zebrafish, providing a comprehensive overview of findings related to energy metabolism, calcium signaling, oxidative stress, and apoptosis. The findings show that mitochondrial health is a decisive factor for neurodevelopment and suggest that zebrafish-based models may play a critical role in developing new treatment strategies for neurodevelopmental disorders in the future.
Indexed as
Identifiers
42406186What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.