Evidence map›Paper›PMID 42406202›Full record

ArticleBioresources and bioprocessing2026

Solvent-driven modulation of phenolic composition and biofunctional activities of three Mentha aquatica formulations: integrated in vitro and in silico insights.

Meryem Tourabi, Amira Metouekel, Mohamed Jeddi, Mohamed Chebaibi, Nesrine Benkhaira, Kawtar Fikri-Benbrahim, Youssouf Ali Younous, Turki M Dawoud, Esmael M Alyami, Hina Ali and 3 more

Abstract read
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In one paragraph

Article in Bioresources and bioprocessing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Meryem TourabiLaboratory of Biotechnology, Conservation and Valorization of Bioresources, Faculty of Sciences, Sidi Mohamed Ben Abdellah University, Fez, Morocco. meryem.tourabi@usmba.ac.ma.
Amira MetouekelSorbonne Universités, Université de Technologie de Compiègne, EA 4297 TIMR, Compiègne, Cedex 60205, France.
Mohamed JeddiMicrobial Biotechnology and Bioactive Molecules Laboratory, Faculty of Science and Techniques, Sidi Mohamed Ben Abdellah University, P.O. Box 2202, Road of Imouzzer, Fez, Morocco.
Mohamed ChebaibiMinistry of Health and Social Protection, Higher Institute of Nursing Professions and Health Techniques, Fez, Morocco.
Nesrine BenkhairaMicrobial Biotechnology and Bioactive Molecules Laboratory, Faculty of Science and Techniques, Sidi Mohamed Ben Abdellah University, P.O. Box 2202, Road of Imouzzer, Fez, Morocco.
Kawtar Fikri-BenbrahimMicrobial Biotechnology and Bioactive Molecules Laboratory, Faculty of Science and Techniques, Sidi Mohamed Ben Abdellah University, P.O. Box 2202, Road of Imouzzer, Fez, Morocco.
Youssouf Ali YounousEvangelical College, BP 1200, N'Djamena, Chad. scientifcresearcher@gmail.com.
Turki M DawoudDepartment of Botany and Microbiology, College of Science, King Saud University, P.O. BOX 2455, Riyadh, 11451, Saudi Arabia. tdawoud@ksu.edu.sa.
Esmael M AlyamiResearch Centre for Advanced Materials Science (RCAMS), King Khalid University, Abha, 61413, Saudi Arabia.
Hina AliShanghai Key Laboratory for Molecular Engineering of Chiral Drugs, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, People's Republic of China.
Gehan M ElossailyDepartment of Basic Medical Sciences, ge of Medicine, AlMaarefa University, Diriyah, Riyadh, 13713, Saudi Arabia.
Badiaa LyoussiLaboratory of Biotechnology, Conservation and Valorization of Bioresources, Faculty of Sciences, Sidi Mohamed Ben Abdellah University, Fez, Morocco.
Elhoussine DerwichLaboratory of Biotechnology, Conservation and Valorization of Bioresources, Faculty of Sciences, Sidi Mohamed Ben Abdellah University, Fez, Morocco.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The goal of this work was to examine the effect of different solvents (Water, EtOH 70%, and acetone) on the phenolic composition, antioxidant, and antibacterial capacity of Moroccan Mentha aquatica L. leaf extract. To this end, HPLC-ESI-FULL-MS was used to characterize the extracts, while the Folin-Ciocalteu and aluminum trichloride techniques were used to evaluate the total phenolic and flavonoid contents. To assess the antibacterial capacity, the microdilution technique was performed to calculate the minimal inhibition concentration (MIC), and minimal bactericidal concentration (MBC). Phytochemical profiling revealed that the extracts were rich in bioactive constituents, particularly ferulic acid derivative, caffeoyl-protocatechuic acid derivative, quercetin, and diosmetin 7-O-beta-D-glucuronide. The hydroethanolic extract contained the highest levels of total phenolic (62.2 ± 1.2 mg GAE/g DW) and flavonoid (29.15 ± 0.09 mg QE/g DW) contents, exceeding those of the acetonic extract (22.2 ± 0.6 and 10.17 ± 0.07 mg GAE/g DW, respectively) and the water extract (22.4 ± 0.6 and 10.9 ± 0.6 mg QE/g DW, respectively). This extract also showed the strongest antioxidant effect, recording an IC

Indexed as

Antibacterial activityAntioxidant activityHPLC-ESI-FULL-MS in-silico approachMentha aquaticaSolvent polarity

Identifiers

PMID42406202
PMCPMC13337976

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.