Evidence map›Paper›PMID 42406909›Full record

ArticleEuropean stroke journal2026

Incidence, clinical characteristics and outcome of spontaneous cerebellar intracerebral haemorrhage in a Norwegian population.

Silje Holt Jahr, Nojoud Koubaa, Vigdis Hillestad, Kristin Tveitan Larsen, Maiken Nordahl Selseth, Trine Lied-Herland, Jarle Sundseth, Else Charlotte Sandset, Ole Morten Rønning, Espen Saxhaug Kristoffersen

Registry-linked trialAbstract read
In one paragraph

Article in European stroke journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05378490 (The Akershus Study of Ischemic Stroke and Thrombolysis -1), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05378490 recruitingnot on this map

The Akershus Study of Ischemic Stroke and Thrombolysis -1 (ASIST-1) Epidemiology, Clinical and Radiological Presentation and Treatment of Cerebrovascular Disease and Stroke Mimics in a Norwegian Population

TypeobservationalSponsorUniversity Hospital, AkershusRan2012 to 2040Enrolled6,000ConditionsStroke, Acute, Intracerebral Hemorrhage, Stroke, Ischemic, TIA
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Silje Holt JahrDepartment of Neurology, Akershus University Hospital, Lørenskog, Norway.ORCID 0000-0003-3008-5159
Nojoud KoubaaDepartment of Neurology, Akershus University Hospital, Lørenskog, Norway.
Vigdis HillestadDepartment of Diagnostic Imaging, Akershus University Hospital, Lørenskog, Norway.
Kristin Tveitan LarsenDepartment of Neurology, Akershus University Hospital, Lørenskog, Norway.
Maiken Nordahl SelsethInstitute of Clinical Medicine, University of Oslo, Oslo, Norway.
Trine Lied-HerlandInstitute of Clinical Medicine, University of Oslo, Oslo, Norway.
Jarle SundsethDepartment of Neurosurgery, Oslo University Hospital, Oslo, Norway.
Else Charlotte SandsetDepartment of Neurology, Oslo University Hospital, Oslo, Norway.ORCID 0000-0003-4312-4778
Ole Morten RønningDepartment of Neurology, Akershus University Hospital, Lørenskog, Norway.
Espen Saxhaug KristoffersenDepartment of Neurology, Akershus University Hospital, Lørenskog, Norway.ORCID 0000-0002-8999-5424

Funding

Akershus University HospitalUniversity of Oslo
6 · The paper itself

Abstract

introductionCerebellar ICH accounts for 5%-10% of spontaneous ICH, yet cerebellar-specific incidence data are sparse and the unselected clinical spectrum and outcomes remain poorly characterised. PATIENTS AND

methodsWe retrospectively identified all adults (≥18 years) in the catchment area of a Norwegian stroke centre with spontaneous cerebellar ICH between 2009 and 2024, using discharge codes and radiological verification. We calculated crude and age-standardised incidence rates with 95% CIs, and assessed clinical characteristics, functional outcome (mRS) and mortality to 1 year.

resultsAmong 129 admissions (median age 75 years; 47% women), 120 were incident cases. Age-standardised incidence was 2.6 per 100,000 person-years (95% CI, 2.1-3.0), rising from 0.3 at < 55 to 21.0 at ≥ 85 years, and remained stable over 16 years (incidence rate ratio 0.97/year; 0.93-1.00). Median haematoma volume was 8.1 mL (mean 11.2 mL); one-third were anticoagulated; 13% underwent neurosurgery. Care limitation was frequent (45%; 64% aged ≥ 75). In-hospital mortality was 31% and 1-year mortality 41%; median time to death was 3 days. At 3 months, 29% achieved functional independence (mRS 0-2), and 36% when restricted to early-phase survivors (>3 days). DISCUSSION: Compared with tertiary surgical series, this unselected cohort had smaller haematomas and a lower surgical rate. Frequent care limitation in older patients reflects clinical reality outside referral centres.

conclusionsCerebellar ICH is rare, with an age gradient mirroring that of ICH overall. Although prognosis is dominated by early deaths, 1 in 3 acute-phase survivors regain functional independence, indicating that outcome is not uniformly poor. CLINICAL

trial registrationClinicalTrials.gov, NCT05378490.

Indexed as

Cerebellar DiseasesCerebral HemorrhageAdultAgedAged, 80 and overCerebellumFemaleHospital MortalityHumansIncidenceMaleMiddle AgedNorwayRetrospective StudiesTreatment Outcomeage-standardised ratecase fatalityepidemiologymortalityposterior fossastroke

Identifiers

PMID42406909
PMCPMC13335647

What Socratic holds

Textmetadata
LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.