Evidence map›Paper›PMID 42410497›Full record

Trial reportBMC anesthesiology2026

Ultrasound guided external oblique intercostal plane block versus posterior transversus abdominis plane block for postoperative analgesia in adult patients undergoing open nephrectomy: a randomized trial.

Amgad Elshikh, Lashin S Ali, Mohammed S ElSharkawy, Sameh M Fathy, Bahaa G Mohamed, Khaled Hamama, Mahmoud A Elmohasseb, Eman H Abu Shanab, Zainab T Ragab, Saad A Moharam and 1 more

Registry-linked trialAbstract readRandomized Controlled TrialComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC anesthesiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06452238 (External Oblique Intercostal Plane Block Versus Ultrasound Guided Transversus Abdominis Plane Block for Postoperative Analgesia in Adult Patients Undergoing Open Nephrectomy), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06452238 nacompletednot on this map

External Oblique Intercostal Plane Block Versus Ultrasound Guided Transversus Abdominis Plane Block for Postoperative Analgesia in Adult Patients Undergoing Open Nephrectomy

TypeinterventionalSponsorTanta UniversityRan2024 to 2025Enrolled40ConditionsExternal Oblique Intercostal Plane Block, Transversus Abdominis Plane Block, Postoperative Analgesia, NephrectomyArmsExternal Oblique Intercostal Plane Block, Transversus Abdominis Plane Block
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Amgad ElshikhAnesthesiology, surgical ICU, and Pain management Department, Faculty of Medicine , Tanta University, Tanta, Egypt.
Lashin S AliBasic Medical Science Department, Faculty of Dentistry, Al-Ahliyya Amman University, Amman, Jordan.
Mohammed S ElSharkawyAnesthesiology, surgical ICU, and Pain management Department, Faculty of Medicine , Tanta University, Tanta, Egypt. mselsharkawy@med.tanta.edu.eg.ORCID http://orcid.org/0000-0003-0814-6728
Sameh M FathyAnesthesiology, surgical ICU, and Pain management Department, Faculty of Medicine , Tanta University, Tanta, Egypt.
Bahaa G MohamedAnesthesia, ICU and Pain Management Department, South Egypt Cancer Institute, Assiut University, Assiut, Egypt.
Khaled HamamaAnesthesiology, surgical ICU, and Pain management Department, Faculty of Medicine , Tanta University, Tanta, Egypt.
Mahmoud A ElmohassebAnesthesiology, surgical ICU, and Pain management Department, Faculty of Medicine , Tanta University, Tanta, Egypt.
Eman H Abu ShanabAnesthesiology, surgical ICU, and Pain management Department, Faculty of Medicine , Tanta University, Tanta, Egypt.
Zainab T RagabAnesthesiology, surgical ICU, and Pain management Department, Faculty of Medicine , Tanta University, Tanta, Egypt.
Saad A MoharamAnesthesiology, surgical ICU, and Pain management Department, Faculty of Medicine , Tanta University, Tanta, Egypt.
Ahmed F MadyAnesthesiology, surgical ICU, and Pain management Department, Faculty of Medicine , Tanta University, Tanta, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNephrectomy procedures result in considerable postoperative discomfort, and limitations on the use of traditional management include opioid-related adverse effects and epidural-associated side effects. A prospective comparison was conducted to evaluate the relative effectiveness of two regional anesthetic techniques, the external oblique intercostal plane block (EOIPB) and the ultrasound-guided posterior transversus abdominis plane block (TAPB), in reducing postsurgical pain after open nephrectomy (OPN).

methodsForty adults who underwent elective OPN were included in the study. The study population was randomly divided into two groups to receive either EOIPB or TAPB in a volume of 20 mL with 0.5% bupivacaine after the induction phase. The primary outcome was cumulative 24-hour pethidine consumption. Secondary outcomes included intraoperative fentanyl requirements, time to first rescue analgesia, pain scores at 0, 4, 8, 12, 18, and 24 h postoperatively, hemodynamic parameters, adverse events, and patient satisfaction.

resultsThe EOIPB group had significantly lower pain scores at 4, 8, 12, and 18 h after surgery compared to the TAPB group (p < 0.05). The EOIPB group used significantly less pethidine than the other group (61.5 ± 24.77 mg vs. 114 ± 12.31 mg, p < 0.001), and it took them longer to receive their first rescue analgesia (7.25 ± 0.91 vs. 6.1 ± 1.55 h, p = 0.007). The EOIPB group exhibited significantly higher patient satisfaction (p = 0.045), although the two groups had similar profiles of adverse events.

conclusionsIn adults undergoing OPN, EOIPB provided superior early postoperative analgesia compared to TAPB during the first 18 h after surgery, as evidenced by lower pain scores, reduced opioid requirements, delayed time first to rescue analgesia, and higher patient satisfaction. Both blocks demonstrated comparable safety profiles. CLINICAL TRIAL: Registration occurring at ClinicalTrials.gov (ID: NCT06452238), (URL: https://clinicaltrials.gov/study/NCT06452238?cond=NCT06452238&rank=1 ), Date: (30-5-2024).

Indexed as

NephrectomyNerve BlockPostoperative PainUltrasonography, InterventionalAbdominal MusclesAdultAgedAnalgesics, OpioidAnesthetics, LocalBupivacaineFemaleHumansMaleMeperidineMiddle AgedPain MeasurementAnalgesics, OpioidAnesthetics, LocalBupivacaineMeperidineExternal oblique intercostal plane blockNephrectomyPostoperative analgesiaRegional anesthesiaTransversus abdominis plane blockUltrasound-guided, regional anesthesia

Identifiers

PMID42410497
PMCPMC13339846

What Socratic holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.