ArticleMedicine2026
The 100 top-cited articles in gout: A bibliometric analysis.
Article in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNumerous studies have investigated gout; however, a focused bibliometric evaluation of the most influential publications remains limited. This study identified and analyzed the top 100 most-cited articles on gout.
methodsThe Web of Science Core Collection Science Citation Index Expanded database was searched using the term "gout." Articles published from January 1, 2000 to April 30, 2026 were screened. The top 100 most-cited articles were selected, and data on citation rank, publication year, journal, impact factor, country, institution, author, study type, research topic, and keywords were extracted. Bibliometric analyses were performed to characterize publication patterns and research trends.
resultsThe most-cited article was published in 2006 and received 4359 citations. The top 100 articles were published in 34 journals, with Annals of the Rheumatic Diseases contributing the largest proportion. The United States was the leading contributing country. The University of Pennsylvania was the most productive institution, and Choi HK was the most prolific author. Observational studies were the most common study design. Keyword co-occurrence analysis identified 4 major research domains: epidemiology, pathophysiological mechanisms, pain management, and comorbidities. Frequently occurring keywords included hyperuricemia, gout, management, risk, arthritis, uric acid, prevalence, coronary heart disease, quality of life, and febuxostat.
conclusionThis bibliometric analysis summarizes the most influential publications in gout research from 2000 to 2026. Major research priorities have shifted from serum urate, diagnosis, and pharmacological treatment toward risk assessment, long-term outcomes, disease burden, and comprehensive management. Hyperuricemia and urate-lowering therapy remain central themes, while emerging topics such as gut microbiota suggest increasing interest in multidisciplinary and precision approaches to gout care.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.