Evidence mapPaperPMID 42411798Full record

ArticleArchiv der Pharmazie2026

1,2,3-Triazole-Linked Chalcones as Privileged Scaffolds in Anticancer Agents.

Sumeyya Koldas, Guler Yagiz Erdemir, Ahsen Kilic, Neslisah Barlak, Omer Faruk Karatas, Aliye Altundas

Abstract readComparative Study
In one paragraph

Article in Archiv der Pharmazie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sumeyya KoldasDepartment of Chemistry, Faculty of Science, Gazi University, Ankara, Türkiye.
Guler Yagiz ErdemirDepartment of Chemistry, Faculty of Science, Gazi University, Ankara, Türkiye.ORCID https://orcid.org/0000-0003-2784-6391
Ahsen KilicDepartment of Molecular Biology and Genetics, Erzurum Technical University, Erzurum, Türkiye.
Neslisah BarlakDepartment of Molecular Biology and Genetics, Erzurum Technical University, Erzurum, Türkiye.
Omer Faruk KaratasDepartment of Molecular Biology and Genetics, Erzurum Technical University, Erzurum, Türkiye.
Aliye AltundasDepartment of Chemistry, Faculty of Science, Gazi University, Ankara, Türkiye.

Funding

Gazi Üniversitesi FYL-2023-8706
6 · The paper itself

Abstract

A new series of extended-functionality triazole-substituted chalcone derivatives was synthesized, and their in vitro anti-proliferative and cytotoxic profiles were evaluated using cancer and non-cancer cell models. First, all compounds were screened in the FaDu head and neck squamous cell carcinoma cell line to identify the most active candidates with comparatively lower IC

Indexed as

Antineoplastic AgentsChalconesTriazolesA549 CellsApoptosisCaco-2 CellsCell Line, TumorCell ProliferationCell SurvivalDose-Response Relationship, DrugDrug Screening Assays, AntitumorHumansInhibitory Concentration 50Molecular StructureStructure-Activity RelationshipAntineoplastic AgentsChalconesTriazoles1,2,3‐triazolediesterA549CaCo‐2cancerchalconescytotoxicity

Identifiers

PMID42411798
PMCPMC13339972

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.