Evidence map›Paper›PMID 42412384›Full record

ArticleOdontology2026

Influence of commercial mouth rinses with different formulations on enamel properties during at-home bleaching.

Thalita Novello Coelho, Ana Júlia Gil, Marcos Roberto Lima Benati, Carolina Meneghin Barbosa, Tatiane Cristina Dotta, Waldemir Francisco Vieira-Junior, Renata Siqueira Scatolin, Laura Nobre Ferraz

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Article in Odontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Thalita Novello CoelhoHermínio Ometto Foundation, University of Araras, Araras, São Paulo, Brazil.
Ana Júlia GilHermínio Ometto Foundation, University of Araras, Araras, São Paulo, Brazil.
Marcos Roberto Lima BenatiDepartment of Restorative Dentistry, Faculdade de Odontologia de Piracicaba, Universidade de Campinas, Piracicaba, Brazil.
Carolina Meneghin BarbosaDepartment of Restorative Dentistry, Faculdade de Odontologia de Piracicaba, Universidade de Campinas, Piracicaba, Brazil.
Tatiane Cristina DottaHermínio Ometto Foundation, University of Araras, Araras, São Paulo, Brazil. tatianedotta@usp.br.ORCID http://orcid.org/0000-0001-6376-679X
Waldemir Francisco Vieira-JuniorDepartment of Restorative Dentistry, Faculdade de Odontologia de Piracicaba, Universidade de Campinas, Piracicaba, Brazil.
Renata Siqueira ScatolinHermínio Ometto Foundation, University of Araras, Araras, São Paulo, Brazil.
Laura Nobre FerrazHermínio Ometto Foundation, University of Araras, Araras, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dental bleaching is a widely used esthetic procedure often associated with oral hygiene products such as mouth rinses. However, the effects of different mouth rinse formulations on enamel during bleaching remain unclear. This study evaluated in vitro the properties of dental enamel exposed to mouth rinses with different active ingredients during at-home bleaching with 10% carbamide peroxide. Bovine enamel-dentin discs were randomly assigned to four groups (n=12): distilled water (DW, control), Listerine Cool Mint Zero Alcohol (CMZ, essential oils), Listerine Cool Mint (CM, essential oils + alcohol), and Listerine Whitening Extreme (WE, essential oils + alcohol + hydrogen peroxide). Bleaching was performed for 4 h/day for 14 days, and mouth rinses were applied twice daily. Color parameters (ΔL* ,Δa*, Δb*, ΔE, ΔE), surface roughness (Ra), and microhardness (KHN) were evaluated at baseline and after treatment. Surface morphology was analyzed by scanning electron microscopy (SEM). Data were analyzed using linear mixed models, generalized linear mixed models, and Kruskal-Wallis tests (α=0.05). No significant differences among groups were observed for color change or surface roughness (p›0.05). All groups showed a significant reduction in microhardness over time (p‹0.05). CMZ and CM exhibited the greatest decrease in microhardness at the final evaluation, differing significantly from the other groups (p‹0.05). SEM images revealed similar surface alterations in all groups, including porosity and depressions. Mouth rinses did not affect bleaching effi cacy or enamel color. Although enamel microhardness, roughness, and morphology changed after bleaching, only microhardness and morphological alterations were influenced by the active ingredients of the mouth rinses. CLINICAL RELEVANCE: The use of mouth rinses during at-home bleaching with carbamide peroxide does not compromise the bleaching efficacy. However, it may adversely affect the properties of dental enamel.

Indexed as

Carbamide peroxideDental enamelMouth rinsesTooth bleaching

Identifiers

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Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.