Evidence map›Paper›PMID 42412651›Full record

ArticleAmerican journal of physiology. Renal physiology2026

Mechanistic target of rapamycin complex-1 plays a role in inhibiting kidney K

Jun-Ya Zheng, Xin-Peng Duan, Wen-Hui Wang, Dao-Hong Lin

Abstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jun-Ya ZhengDepartment of Endocrinology and Metabolism, Peking University People's Hospital, Beijing, People's Republic of China.
Xin-Peng DuanDepartment of Physiology, School of Basic Medical Sciences, Xuzhou Medical University, Xuzhou, People's Republic of China.
Wen-Hui WangDepartment of Pharmacology, New York Medical College, Valhalla, New York, United States.ORCID 0000-0002-7503-9554
Dao-Hong LinDepartment of Pharmacology, New York Medical College, Valhalla, New York, United States.ORCID 0000-0003-1760-2684

Funding

Role of Kir4.1 in regulating NCC and ROMK in DCTR01DK133220 · NIDDK · NEW YORK MEDICAL COLLEGE · PI ELLISON, DAVID HOADLEY, WANG, WENHUI · 2022 to 2025
$2.6M
Regulation of Kir4.1/Kir5.1 and renal potassium excretionR01DK136491 · NIDDK · NEW YORK MEDICAL COLLEGE · PI Dao-Hong Lin · 2023 to 2026
$1.4M
HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) DK133220HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) DK136491NIDDK NIH HHS R01 DK133220NIDDK NIH HHS R01 DK136491
6 · The paper itself

Abstract

Decreased dietary K

Indexed as

KidneyKidney Tubules, DistalMechanistic Target of Rapamycin Complex 1PotassiumPotassium, DietaryRenal EliminationAnimalsEpithelial Sodium ChannelsFemaleKcnj10 ChannelKidney Tubules, CollectingKir5.1 ChannelMaleMiceMice, KnockoutPotassium Channels, Inwardly RectifyingEpithelial Sodium ChannelsKcnj10 ChannelKcnj16 protein, mouseKcnj1 protein, mouseKir5.1 ChannelMechanistic Target of Rapamycin Complex 1PotassiumPotassium Channels, Inwardly RectifyingPotassium, DietaryRegulatory-Associated Protein of mTORRptor protein, mouseSlc12a3 protein, mouseSolute Carrier Family 12Solute Carrier Family 12, Member 3ENaCKir4.1/Kir5.1NCCRAPTORROMK

Identifiers

PMID42412651
PMCPMC13402032

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.