Evidence map›Paper›PMID 42412839›Full record

ArticleBioinformatics (Oxford, England)2026

AutoPCR: automated phenotype concept recognition by prompting.

Yicheng Tao, Yuanhao Huang, Yiqun Wang, Xin Luo, Jie Liu

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yicheng TaoDepartment of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, MI 48109, United States.ORCID 0000-0001-9615-4976
Yuanhao HuangGilbert S. Omenn Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, United States.ORCID 0000-0002-8878-1520
Yiqun WangGilbert S. Omenn Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, United States.ORCID 0009-0004-4157-9407
Xin LuoGilbert S. Omenn Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, United States.ORCID 0009-0005-5335-3031
Jie LiuDepartment of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, MI 48109, United States.ORCID 0000-0002-9504-0587

Funding

PanKbase: a community hub for integrated pancreas knowledgeU24DK138515 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Marcela Brissova, Jean-Philippe Cartailler · 2024 to 2026
$11.3M
Co-designing Ethical Multimodal AI Systems for Mapping T1D ProgressionOT2OD038003 · OD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Marcela Brissova, Kai-Wei Chang · 2025 to 2026
$4.0M
NIDDK NIH HHS U24 DK138515NIH HHS OT2 OD038003NIH HHS OT2OD038003NIH HHS U24DK138515
6 · The paper itself

Abstract

motivationPhenotype concept recognition (CR) is a fundamental task in biomedical text mining. However, existing methods either require ontology-specific training, making them struggle to generalize across diverse text styles and evolving biomedical terminology, or depend on general-purpose large language models that lack necessary domain knowledge.

resultsTo address these limitations, we propose AutoPCR, a prompt-based phenotype CR method designed to automatically generalize to new ontologies and unseen data without ontology-specific training. To further boost performance, we also introduce an optional self-supervised training strategy. Experiments show that AutoPCR achieves the best average and most robust performance across datasets. Further ablation and transfer studies demonstrate its inductive capability and generalizability to new ontologies. AVAILABILITY AND IMPLEMENTATION: Our code is available at https://github.com/yctao7/AutoPCR.

Indexed as

Data MiningPhenotypeSoftwareAlgorithmsBiological Ontologies

Identifiers

PMID42412839
PMCPMC13340160

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.