Evidence map›Paper›PMID 42414212›Full record

ArticleeNeuro2026

c-Maf Deletion in Cortical Somatostatin, But Not Parvalbumin, Interneurons Leads to Absence-Like Epileptiform Activity in Mice.

Morgane A Leroux, Jia Sheng Hu, Yuliya Voskobiynyk, Emily Ling-Lin Pai, Irene Lew, Marie Burkart, John L R Rubenstein, Jeanne T Paz

Abstract read
In one paragraph

Article in eNeuro, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Morgane A LerouxGladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, California 94158.
Jia Sheng HuDepartment of Psychiatry, University of California San Francisco, San Francisco, California 94158.
Yuliya VoskobiynykGladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, California 94158.ORCID https://orcid.org/0000-0003-4169-3002
Emily Ling-Lin PaiDepartment of Psychiatry, University of California San Francisco, San Francisco, California 94158.
Irene LewGladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, California 94158.
Marie BurkartGladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, California 94158.
John L R RubensteinDepartment of Psychiatry, University of California San Francisco, San Francisco, California 94158 john.rubenstein@ucsf.edu jeanne.paz@gladstone.ucsf.edu.ORCID https://orcid.org/0000-0002-4414-7667
Jeanne T PazGladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, California 94158 john.rubenstein@ucsf.edu jeanne.paz@gladstone.ucsf.edu.ORCID https://orcid.org/0000-0001-6339-8130

Funding

Genetic Control of Basal Telencephalic DevelopmentR01MH081880 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RUBENSTEIN, JOHN L. R. · 2009 to 2023
$8.1M
Genetic Regulation of Telencephalon DevelopmentR37MH049428 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RUBENSTEIN, JOHN L. R. · 2008 to 2017
$5.9M
STRUCTURE, EXPRESSION &FUNCTION OF THE DLX GENE FAMILYR01MH049428 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RUBENSTEIN, JOHN L. R. · 1992 to 2022
$5.8M
Microglial control of thalamocortical circuits in Alzheimer's diseaseK99NS146256 · NINDS · J. DAVID GLADSTONE INSTITUTES · PI Yuliya Voskobiynyk · 2026 to 2026
$123k
NIMH NIH HHS R01 MH049428NIMH NIH HHS R01 MH081880NIMH NIH HHS R37 MH049428NINDS NIH HHS K99 NS146256
6 · The paper itself

Abstract

Mafb and c-Maf transcription factors (TFs) are expressed in medial ganglionic eminence (MGE) lineages, beginning in progenitors and continuing into mature GABAergic parvalbumin-positive (PV

Indexed as

Cerebral CortexEpilepsyInterneuronsMafB Transcription FactorParvalbuminsProto-Oncogene Proteins c-mafSomatostatinAnimalsDisease Models, AnimalFemaleMaleMiceMice, TransgenicMafb protein, mouseMafB Transcription FactorMaf protein, mouseParvalbuminsProto-Oncogene Proteins c-mafSomatostatinabsence epilepsycortical developmentelectrophysiologyinterneuronsspike and wave discharges

Identifiers

PMID42414212
PMCPMC13395531

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.