Evidence map›Paper›PMID 42414213›Full record

ArticleeNeuro2026

Complex Three-Dimensional Rearing Environments Amplify Compensatory Plasticity Following Early Blindness.

Deepa L Ramamurthy, Mackenzie Englund, Tanner J Kovacs, Heather Dodson, Leah A Krubitzer

Abstract read
In one paragraph

Article in eNeuro, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Deepa L RamamurthyCenter for Neuroscience, University of California, Davis, California 95618 deepar@ucr.edu.ORCID https://orcid.org/0000-0003-4064-5148
Mackenzie EnglundCenter for Neuroscience, University of California, Davis, California 95618.
Tanner J KovacsCenter for Neuroscience, University of California, Davis, California 95618.
Heather DodsonCenter for Neuroscience, University of California, Davis, California 95618.
Leah A KrubitzerCenter for Neuroscience, University of California, Davis, California 95618.

Funding

Cross modal plasticity following loss of vision at different developmental stages: Cortical function, connections and compensatory behaviorR01EY034303 · NEI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KRUBITZER, LEAH ANN · 2022 to 2025
$1.5M
NEI NIH HHS R01 EY034303
6 · The paper itself

Abstract

The neocortex has a remarkable capacity to alter its functional organization and connectivity in response to sensory loss, particularly if this loss occurs early in life. A key question is whether this cross-modal reorganization is driven by sensory deprivation or by enhanced use of the spared senses. We investigated how different rearing environments shape neural responses in primary somatosensory cortex (S1) of short-tailed opossums (

Indexed as

BlindnessEnvironmentNeuronal PlasticitySomatosensory CortexAnimalsExploratory BehaviorFemaleMaleMonodelphisNeuronsSensory DeprivationTouch PerceptionVibrissaecompensatory plasticitycross-modal plasticityenvironmental enrichmenttouchvibrissavision

Identifiers

PMID42414213
PMCPMC13406312

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.