Evidence map›Paper›PMID 42414839›Full record

ArticleAIDS and behavior2026

The Impact of a Household Intervention on ART Adherence and Household HIV Competency for People Living with HIV: Results from a Cluster-Randomised Controlled Trial in Cape Town, South Africa.

Linda S Campbell, Caroline Masquillier, Lucia Knight, Jeroen de Man, Neo Sematlane, Lorraine Tanyaradzwa Dube, Anton Delport, Edwin Wouters

Abstract read
PubMed Publisher
In one paragraph

Article in AIDS and behavior, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Linda S CampbellCentre for Population, Family and Health, University of Antwerp, Prinsstraat 13, Antwerp, 2000, Belgium. linda.campbell@uantwerpen.be.ORCID http://orcid.org/0000-0003-3391-4370
Caroline MasquillierCentre for Population, Family and Health, University of Antwerp, Prinsstraat 13, Antwerp, 2000, Belgium.ORCID http://orcid.org/0000-0003-1748-5967
Lucia KnightDivision of Social and Behavioural Sciences, School of Public Health, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.ORCID http://orcid.org/0000-0001-9938-6887
Jeroen de ManCentre for Population, Family and Health, University of Antwerp, Prinsstraat 13, Antwerp, 2000, Belgium.ORCID http://orcid.org/0000-0002-3196-8757
Neo SematlaneSchool of Public Health, Community and Health Sciences,, University of the Western Cape, Cape Town, South Africa.ORCID http://orcid.org/0000-0001-8511-619X
Lorraine Tanyaradzwa DubeSchool of Public Health, Community and Health Sciences,, University of the Western Cape, Cape Town, South Africa.ORCID http://orcid.org/0000-0002-0340-4014
Anton DelportSchool of Public Health, Community and Health Sciences,, University of the Western Cape, Cape Town, South Africa.ORCID http://orcid.org/0000-0001-5638-7900
Edwin WoutersCentre for Population, Family and Health, University of Antwerp, Prinsstraat 13, Antwerp, 2000, Belgium.ORCID http://orcid.org/0000-0003-2268-3829

Funding

Fonds Wetenschappelijk Onderzoek 12T8119NFonds Wetenschappelijk Onderzoek G046423NVLIRUOS ZA2018TEA474A102VLIRUOS ZA2022TEA527A102
6 · The paper itself

Abstract

In 2023, an estimated 39.9 million people globally were living with HIV, including 7.7 million in South Africa. Adherence to antiretroviral therapy (ART) is crucial for health outcomes, yet remains challenging. Households may shape health behaviours, including ART adherence. This study evaluated a household-level intervention to improve ART adherence in Cape Town, South Africa, which aimed to promote HIV competency for participants and their households. Baseline data were collected from 316 participants in 12 clinics (May 2021 - May 2022), with endline data from 198 participants (December 2021 - July 2022). Cluster-level analysis and mixed-effects models, with multiple imputation and complete case approaches, were utilised. At endline, there was evidence of a difference between control and intervention arms for following the ART schedule (aOR: 3.88, t = 2.62, p = 0.009), and taking ART on time (aOR: 2.28, t = 2.54, p = 0.01). Household-based interventions may have an impact on ART adherence, and should be considered in future adherence research, programming, and interventions. CLINICAL

trial registrationClinical Trial Number: Pan African Clinical Trial Registry, PACTR201906476052236. Registered on 24 June 2019.

Indexed as

AdherenceARTFamilyHIVHouseholdIntervention

Identifiers

PMID42414839

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.