Evidence map›Paper›PMID 42415640›Full record

ArticleJournal of applied toxicology : JAT2026

Biological Effects of Selenium-Containing Ionic Liquids: Cytotoxicity, Mercury Interaction, and Antiproliferative Activity in Glioblastoma Cells.

Guilherme Schmitt Rieder, Alessandro de Souza Prestes, Fernanda D'Avila da Silva, Nilda de Vargas Barbosa, Alix Y Bastidas Ángel, Mariana F Soares, Carolina Martins Fernandes, Maria Anttônia Oliveira Petersen, Manuela Moura Silva, Juliete Nathali Scholl and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of applied toxicology : JAT, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Guilherme Schmitt RiederPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica, ICBS, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul, Brazil.ORCID https://orcid.org/0000-0002-5626-756X
Alessandro de Souza PrestesDepartamento de Bioquímica e Biologia Molecular, Universidade Federal de Santa Maria (UFSM), Santa Maria, Rio Grande do Sul, Brazil.ORCID https://orcid.org/0000-0001-7094-1429
Fernanda D'Avila da SilvaDepartamento de Biomedicina e Núcleo Comum de Saúde, Universidade Regional do Noroeste do Estado do Rio Grande do Sul (UNIJUÍ), Ijuí, Rio Grande do Sul, Brazil.
Nilda de Vargas BarbosaDepartamento de Bioquímica e Biologia Molecular, Universidade Federal de Santa Maria (UFSM), Santa Maria, Rio Grande do Sul, Brazil.
Alix Y Bastidas ÁngelDepartamento de Química, Universidade Federal de Minas Gerais-UFMG, Belo Horizonte, Minas Gerais, Brazil.
Mariana F SoaresDepartamento de Química, Universidade Federal de Minas Gerais-UFMG, Belo Horizonte, Minas Gerais, Brazil.
Carolina Martins FernandesDepartamento de Bioquímica e Biologia Molecular, Universidade Federal de Santa Maria (UFSM), Santa Maria, Rio Grande do Sul, Brazil.
Maria Anttônia Oliveira PetersenDepartamento de Bioquímica e Biologia Molecular, Universidade Federal de Santa Maria (UFSM), Santa Maria, Rio Grande do Sul, Brazil.
Manuela Moura SilvaDepartamento de Bioquímica e Biologia Molecular, Universidade Federal de Santa Maria (UFSM), Santa Maria, Rio Grande do Sul, Brazil.
Juliete Nathali SchollPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica, ICBS, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul, Brazil.
Fabrício FigueiróPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica, ICBS, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul, Brazil.
Pablo Andrei NogaraInstituto Federal de Educação, Ciência e Tecnologia Sul-Rio-grandense (IFSul), Bagé, Rio Grande do Sul, Brazil.
Laura OrianDipartimento di Scienze Chimiche, Università di Padova, Padova, Italy.ORCID https://orcid.org/0000-0002-1673-5111
Eduardo E AlbertoDepartamento de Química, Universidade Federal de Minas Gerais-UFMG, Belo Horizonte, Minas Gerais, Brazil.
Michael AscnherDepartment of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York, USA.ORCID https://orcid.org/0000-0002-2619-1656
Diogo Onofre Gomes de SouzaPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica, ICBS, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul, Brazil.
Debora Guerini de SouzaPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica, ICBS, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul, Brazil.ORCID https://orcid.org/0000-0003-2982-4989
João Batista Teixeira da RochaPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica, ICBS, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul, Brazil.ORCID https://orcid.org/0000-0003-3829-0595

Funding

Mechanisms of Manganese NeurotoxicityR01ES010563 · NIEHS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Michael Aschner, Aaron B Bowman · 2001 to 2026
$11.9M
Alzheimer's Association AARF-D-22-928702Brasil and Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPQ)Brazilian Initiative of Biomarkers for Neurodegenerative Diseases, Ministry of Health of Brazil 30420240118CAPESCNPq 141379/2024-3Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)FAPEMIG APQ-00349-22FAPERGSFINEPINCT/CNPq Neuroprotection (INCT-NeurPro) 408446/2024-2NIEHS NIH HHS R01 ES010563
6 · The paper itself

Abstract

Selenium (Se) is an essential micronutrient that participates in redox regulation and cellular homeostasis. Selenium-containing ionic liquids (ILsSe) have emerged as hybrid compounds combining the properties of organoselenium molecules with the tunable features of ionic liquids. In this study, we evaluated the cytotoxicity, interaction with mercury (Hg

Identifiers

PMID42415640
PMCPMC13489062

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.