Evidence map›Paper›PMID 42415925›Full record

ArticleAlzheimer's & dementia. Behavior & socioeconomics of aging2025

Age at immigration and cognitive aging in those with exceptional longevity, does timing matter? The LifeAfter90 Study.

Claire C Meunier, Maria M Corrada, Paola Gilsanz, Kristen M George, Claudia H Kawas, Dan Mungas, Charles DeCarli, Oanh L Meyer, Alexander Ivan B Posis, Rachel A Whitmer

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Alzheimer's & dementia. Behavior & socioeconomics of aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Claire C MeunierDepartment of Public Health Sciences, University of California Davis, University of California Davis Medical Sciences 1-C, One Shields Avenue, Davis, CA 95616, USA.
Maria M CorradaDepartment of Neurology, University of California Irvine, 200 S. Manchester Ave. Ste. 206, Irvine, CA 92697, USA.
Paola GilsanzDivision of Research, Kaiser Permanente Northern California, 2000 Broadway, Oakland, CA 94612, USA.
Kristen M GeorgeDepartment of Public Health Sciences, University of California Davis, University of California Davis Medical Sciences 1-C, One Shields Avenue, Davis, CA 95616, USA.
Claudia H KawasDepartment of Neurology, University of California Irvine, 200 S. Manchester Ave. Ste. 206, Irvine, CA 92697, USA.
Dan MungasDepartment of Neurology, University of California Davis, 1651 Alhambra Blvd, Ste. 200, Sacramento, CA 95817, USA.
Charles DeCarliDepartment of Neurology, University of California Davis, 1651 Alhambra Blvd, Ste. 200, Sacramento, CA 95817, USA.
Oanh L MeyerDepartment of Neurology, University of California Davis, 1651 Alhambra Blvd, Ste. 200, Sacramento, CA 95817, USA.
Alexander Ivan B PosisDepartment of Public Health Sciences, University of California Davis, University of California Davis Medical Sciences 1-C, One Shields Avenue, Davis, CA 95616, USA.
Rachel A WhitmerDepartment of Public Health Sciences, University of California Davis, University of California Davis Medical Sciences 1-C, One Shields Avenue, Davis, CA 95616, USA.

Funding

Epidemiology of Age-related Dementia, Mild Cognitive Impairment and Brain Pathology in Cohort of Oldest-OldR01AG056519 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Maria Corrada, Paola Gilsanz · 2022 to 2026
$25.8M
UC Davis Alzheimer's Disease Research CenterP30AG072972 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Charles DeCarli, Rachel A Whitmer · 2021 to 2026
$25.2M
NIA NIH HHS P30 AG072972NIA NIH HHS R01 AG056519
6 · The paper itself

Abstract

introductionThe role of immigration on brain health in the oldest-old is not well understood. We evaluated how nativity and age at immigration were associated with cognition in a diverse cohort aged ≥90.

methodsLifeAfter90 is an ongoing longitudinal study of adults aged ≥90 years with domain-specific cognition assessed every 6-months. Linear regression and linear mixed models examined associations of nativity and age at immigration, pooled across countries, with cognitive function and change adjusted for demographic variables.

resultsAmong 896 participants, non-US-born individuals had lower baseline executive function (EF) (β(95%

conclusionThese findings suggest that despite exceptional longevity, timing of immigration may impact risk for cognitive impairment after age 90.

Indexed as

agingCognitiondementiaimmigrationninetyoldest-old

Identifiers

PMID42415925
PMCPMC13340874

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.