Evidence map›Paper›PMID 42415986›Full record

ReviewFrontiers in cardiovascular medicine2026

Myocardial inflammation in myocarditis: mechanisms and therapeutic targets.

Cristina Madaudo, Daniela Di Lisi, Francesca Macaione, Vincenzo Nuzzi, Andrea Micarelli, Giusy Sausa, Giovanni Castelli, Egle Corrado, Alfredo Ruggero Galassi, Giuseppina Novo

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Cristina MadaudoDepartment of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (ProMISE), University of Palermo, Palermo, Italy.
Daniela Di LisiDivision of Cardiology, University Hospital P. Giaccone, University of Palermo, Palermo, Italy.
Francesca MacaioneDivision of Cardiology, University Hospital P. Giaccone, University of Palermo, Palermo, Italy.
Vincenzo NuzziDepartment of Clinical Cardiology and Heart Failure, Mediterranean Institute for Transplantation and Advanced Specialized Therapies, IRCCS ISMETT, UPMC, Palermo, Italy.
Andrea MicarelliDepartment of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (ProMISE), University of Palermo, Palermo, Italy.
Giusy SausaDepartment of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (ProMISE), University of Palermo, Palermo, Italy.
Giovanni CastelliDivision of Cardiology, University Hospital P. Giaccone, University of Palermo, Palermo, Italy.
Egle CorradoDepartment of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (ProMISE), University of Palermo, Palermo, Italy.
Alfredo Ruggero GalassiDepartment of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (ProMISE), University of Palermo, Palermo, Italy.
Giuseppina NovoDepartment of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (ProMISE), University of Palermo, Palermo, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myocarditis is an inflammatory disease of the myocardium with heterogeneous aetiologies, in which innate and adaptive immune responses critically influence clinical outcomes, ranging from complete recovery to progression toward dilated cardiomyopathy. In viral myocarditis, pathogen- and damage-associated molecular patterns activate pattern-recognition receptors, triggering NF-

Indexed as

immunomodulatory therapyinflammationinflammation-guided risk stratificationinnate and adaptive immunitymyocarditis

Identifiers

PMID42415986
PMCPMC13337714

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.