Evidence mapPaperPMID 42416144Full record

ArticleOpen medicine (Warsaw, Poland)2026

Aloe emodin attenuates Aβ

Fang Huang, Mingxing Guo, Yiran Yang, Zhizhong Wang

Abstract read
In one paragraph

Article in Open medicine (Warsaw, Poland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fang HuangDepartment of Traditional Chinese Medicine, Wuhan Central Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430014, China.ORCID https://orcid.org/0009-0002-9612-9994
Mingxing GuoDepartment of Traditional Chinese Medicine, Wuhan Central Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430014, China.ORCID https://orcid.org/0009-0009-4291-1578
Yiran YangDepartment of Traditional Chinese Medicine, Wuhan Central Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430014, China.ORCID https://orcid.org/0009-0002-3592-9314
Zhizhong WangCollege of Chinese Medicine, Hubei University of Chinese Medicine, Wuhan, 430033, China.ORCID https://orcid.org/0009-0008-1900-8498

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To study the role and underlying mechanism of aloe emodin, a natural anthraquinone compound known for antioxidant, and anti-inflammatory activities, in Alzheimer's disease (AD). Methods: Aβ Results: Bioinformatics analysis revealed that PPM1K is significantly upregulated in AD and showed predicted in silico binding with aloe emodin. Aloe emodin markedly improved the viability of Aβ Conclusions: Aloe emodin alleviates Aβ

Indexed as

aloe emodinAlzheimer’s diseaseAβ1–42PPM1KSH-SY5Y

Identifiers

PMID42416144
PMCPMC13340830

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.