ArticleFrontiers in neurology
Endovascular thrombectomy in selected patients with active cancer and thrombocytopenia: outcomes under an institutional platelet transfusion practice.
Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background and purpose: Thrombocytopenia is common in patients with active cancer and large vessel occlusion (LVO), raising safety concerns regarding endovascular thrombectomy (EVT). Therefore, we compared the procedural safety and clinical outcomes of EVT between patients with active cancer with and without thrombocytopenia. Methods: This retrospective multicenter study analyzed patients with active cancer who underwent EVT for anterior-circulation LVO between 2017 and 2024. Patients were categorized according to the presence of thrombocytopenia (<150 × 10 Results: Among 98 patients with active cancer undergoing EVT, PSM yielded 40 balanced pairs. Rates of hemorrhagic complications were numerically similar between the groups, with no statistically significant differences observed in HT ( Conclusion: In this exploratory study of selected patients with active cancer undergoing EVT for anterior-circulation LVO, thrombocytopenia was not associated with a statistically demonstrable increase in hemorrhagic complications. However, these findings should be interpreted cautiously because of limited event numbers, residual confounding, and the absence of an untreated thrombocytopenic comparator group.
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