ArticleFrontiers in bioengineering and biotechnology2026
Germanium-embedded bioactive fabric reduces bacterial bioburden and modulates fibroblast and macrophage behavior
Article in Frontiers in bioengineering and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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7 authors.
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Abstract
Introduction: Surgical site infections (SSIs) occur in 2%-4% of all surgical cases. Wearable bioactive fabrics (BAFs) containing semiconductor germanium are reported to promote microcirculation, enhance immunity, and increase antibacterial activity, with the potential to improve outcomes in SSIs. While BAFs are proposed to exert their effects through the generation of negative ions and the emission of far-infrared radiation, their mechanism of action has not been fully explored. The objective of this study was to evaluate the impact of BAFs on bacterial bioburden, fibroblast migration and proliferation, and inflammation modulation in the context of SSIs. Methods: Utilizing an Results: BAF exposure reduced Discussion: Exposure to BAFs exhibited direct and indirect bactericidal effects, enhanced fibroblast migration, reduced fibroblast proliferation, increased immunomodulatory cytokine secretion, and altered macrophage gene expression in ways that may positively impact wound healing. BAFs warrant further
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