Evidence map›Paper›PMID 42416822›Full record

ArticleFrontiers in pharmacology2026

Jujuboside A extends healthspan and enhances resistance of oxidative stress in

Yunliang Cao, Shuangjie Ren, Xiaocong Li, Xin Xiao, Yi Xiao

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yunliang Cao *Department of Oncology, The Second Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Shuangjie Ren *The Key Lab of Guizhou Provincial Department of Education for Medical Prevention and Treatment of Tumor, Zunyi Medical University, Zunyi, Guizhou, China.
Xiaocong Li *The First People's Hospital of Zunyi, The Third Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China.
Xin XiaoInstitute of life sciences, Zunyi Medical University, Zunyi, Guizhou, China.
Yi XiaoThe Key Lab of Guizhou Provincial Department of Education for Medical Prevention and Treatment of Tumor, Zunyi Medical University, Zunyi, Guizhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Jujuboside A (JA) is a biologically active saponin primarily extracted from sour jujube seeds. Existing studies have demonstrated that JA plays significant roles in anti-inflammatory, antioxidant, neuroprotective, and metabolic regulation. However, its mechanisms in lifespan extension and antioxidation remain to be further elucidated. In this study, we found that JA extended the lifespan of

Indexed as

Caenorhabditis elegansDAF-16/FOXO3Ahealthspanjujuboside Aoxidative stressSKN-1/Nrf2

Identifiers

PMID42416822
PMCPMC13337699

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.