Evidence map›Paper›PMID 42416853›Full record

ArticleCognitive therapy and research2024

Shift in Valence Bias Associated with Decrease in Trait Anxiety and Depression Symptoms.

Nicholas R Harp, R James R Blair, Maital Neta

Abstract read
In one paragraph

Article in Cognitive therapy and research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Facing ambiguity: What we do in the space between stimulus and response.Current directions in psychological science · 2026
    Article
  2. Article
  3. Chronic Stress May Amplify Gender/Sex Differences in Amygdala Reactivity to Ambiguous Emotional Stimuli.Stress and health : journal of the International Society for the Investigation of Stress · 2025
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nicholas R HarpDepartment of Psychiatry, Yale University, Suite 701, 7th Floor, 1 Church St, New Haven, CT 06510, USA.ORCID 0000-0002-8115-9309
R James R BlairRegion Hovedstadens Psykiatri Børne og Ungdomspsykiatrisk Center, Genthofte, Hovedstaden, Denmark.
Maital NetaDepartment of Psychology, University of Nebraska-Lincoln, Lincoln, NE, USA.

Funding

Neuroimaging Sciences Training ProgramT32DA022975 · NIDA · YALE UNIVERSITY · PI Graeme F Mason, Rajita Sinha · 2007 to 2026
$5.7M
Functional Brain Networks Mediating Individual Differences in Valence BiasR01MH111640 · NIMH · UNIVERSITY OF NEBRASKA LINCOLN · PI NETA, MAITAL · 2017 to 2022
$1.8M
NIDA NIH HHS T32 DA022975NIMH NIH HHS R01 MH111640
6 · The paper itself

Abstract

Purpose: Mindfulness-Based Stress Reduction (MBSR) is a well-known method for reducing stress and negative affect. Recently, a small, open-label trial showed that MBSR training was associated with a shift toward more positive responses to emotionally ambiguous signals (e.g., surprised expressions that convey either positive or negative meaning). Methods: Here, we test whether the MBSR-induced shift in responses to emotional ambiguity reported previously is accompanied by a reduction in self-reported depression and anxiety symptoms ( Results: In support of our hypothesis, we found that the degree to which individuals' post-training responses to emotional ambiguity became more positive was associated with the degree of reduction in post-training depression and anxiety symptoms (i.e., post-training symptoms controlling for pre-training symptoms; Conclusions: Altogether, the results suggest that shifts in valence bias and reductions in internalizing symptoms track one another following MBSR, warranting future randomized, mechanistic investigations.

Indexed as

Affective processingAnxietyDepressionIndividual differences

Identifiers

PMID42416853
PMCPMC13341176

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.