Evidence map›Paper›PMID 42416963›Full record

ArticleCureus2026

Serum Magnesium Levels Across Clinical Stages of Alcoholic Liver Disease: A Cross-Sectional Study From South India.

Ligin Lavichan, Ramesh Bala Arivazhagan, Selvamuthukumaran S, Prabakaran Vaithinathan, Sridurga Mattyvanan

Abstract read
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ligin LavichanDepartment of General Medicine, Vinayaka Mission's Medical College and Hospital, Vinayaka Mission's Research Foundation (Deemed to be University), Karaikal, IND.
Ramesh Bala ArivazhaganDepartment of General Medicine, Vinayaka Mission's Medical College and Hospital, Vinayaka Mission's Research Foundation (Deemed to be University), Karaikal, IND.
Selvamuthukumaran SDepartment of General Medicine, Vinayaka Mission's Medical College and Hospital, Vinayaka Mission's Research Foundation (Deemed to be University), Karaikal, IND.
Prabakaran VaithinathanDepartment of General Medicine, Vinayaka Mission's Medical College and Hospital, Vinayaka Mission's Research Foundation (Deemed to be University), Karaikal, IND.
Sridurga MattyvananDepartment of Biochemistry, Vinayaka Mission's Medical College and Hospital, Vinayaka Mission's Research Foundation (Deemed to be University), Karaikal, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectiveAlcoholic liver disease (ALD) involves progressive hepatic dysfunction and frequent electrolyte disturbances, but the relationship between serum magnesium and clinically staged ALD remains unclear. This study aimed to explore the relationship between the two with established markers of disease severity. MATERIALS AND

methodsIn this hospital‑based cross‑sectional study, 80 adults with confirmed ALD were enrolled at a tertiary center in Karaikal, TN, IND, between January and December 2025. Patients were classified as non‑cirrhotic ALD, compensated cirrhosis, or decompensated cirrhosis. Clinical evaluation, laboratory tests (including serum magnesium), viral serology, ultrasonography, and the model for end-stage liver disease (MELD) and Maddrey's discriminant function (DF) scores were obtained. Prognostic assessment was performed using the MELD, Maddrey's DF, and the age-bilirubin-INR-creatinine (ABIC) scores.

resultsMost patients had non‑cirrhotic ALD (53.8%) or decompensated cirrhosis (40.0%); nearly all were male. With advancing stages, hemoglobin, platelets, sodium, albumin, and coagulation indices worsened, and MELD and DF scores increased significantly. Serum magnesium showed a progressive, borderline non‑significant decline (p=0.071).

conclusionConventional biochemical markers and prognostic scores robustly reflected ALD severity, while serum magnesium trended downward across stages, suggesting a potential adjunctive role rather than a standalone severity marker.

Indexed as

alcoholic liver diseasebiomarkerscross-sectional studiesliver cirrhosismagnesiumprognosis

Identifiers

PMID42416963
PMCPMC13338987

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.