ArticleCatheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions2026
Impact of Preoperative Nutrition Status on Wound Healing in Patients With Chronic Limb-Threatening Ischemia Undergoing Endovascular Therapy.
Article in Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Impact of Preoperative Nutrition Status on Wound Healing in Patients With Chronic Limb-Threatening Ischemia Undergoing Endovascular Therapy.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026Article
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Abstract
backgroundIn the treatment of chronic limb-threatening Ischemia (CLTI), achieving complete wound healing is a crucial goal. The controlling nutritional status (CONUT) score, prognostic nutritional index (PNI), and geriatric nutritional risk index (GNRI) are objective tools for assessing malnutrition and have been shown to be associated with poor clinical outcomes in patients with CLTI. However, the association between malnutrition, as defined by various tools, and wound healing in patients with CLTI following EVT has not yet been fully evaluated.
aimsThis study aimed to investigate the relationship between malnutrition and wound healing in patients with CLTI undergoing endovascular therapy (EVT).
methodsA total of 165 patients treated with EVT for CLTI with wounds were retrospectively analyzed for up to 12 months of follow-up between January 2016 and June 2024. The patients were classified into two groups based on their wound healing status 6 months postoperatively: early wound healing group and delayed wound healing group. Nutritional status was evaluated using the CONUT score, GNRI, and PNI. The relationship between nutritional status and delayed wound healing was examined using logistic regression analysis.
resultsThe delayed wound healing group had significantly higher CONUT score and lower GNRI and PNI. Logistic regression analysis demonstrated that CONUT malnutrition (odds ratio [OR] 4.140, 95% confidence interval [CI] 1.689-10.150, p = 0.002) and GNRI malnutrition (OR 5.269, 95% CI 1.959-14.171, p = 0.001) were independent predictors of delayed wound healing. Receiver operating characteristic (ROC) analysis indicated that the area under the curve (AUC) for the CONUT score (AUC = 0.811) was greater than that for the GNRI (AUC = 0.763), although no significant differences were found (p = 0.324).
conclusionsMalnutrition is closely associated with delayed wound healing in patients with CLTI following EVT. Nutritional status is crucial for decision-making in the treatment of CLTI, and early nutritional intervention may improve patient outcomes.
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